Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Añadir filtros








Intervalo de año
1.
Journal of Biomedical Engineering ; (6): 798-801, 2005.
Artículo en Chino | WPRIM | ID: wpr-238338

RESUMEN

The aim of this study is to evaluate the effect of Interleukin-6 on cyclophosphamide-induced hematopoietic damnification. The doses of Interleukin-6 in 3 different regimens were hypodermally injected into dogs for 7 days respectively to establish the cyclophosphamide-induced hematopoietic damnification model. The effect of Interleukin-6 on the production of platelets and the amount of other cells in the dogs' bone marrow were determined on the 21st day. The results showed that Interleukin-6 significantly alleviated the reduction of platelet count and recovered the platelets level faster. The impedance effects of Interleukin-6 directed against hematopoietic damnification of bone marrow and spleen were shown by pathological examination. These suggest that the Interleukin-6 can significantly impede cyclophosphamide-induced hematopoietic damnification.


Asunto(s)
Animales , Perros , Femenino , Masculino , Células de la Médula Ósea , Metabolismo , Ciclofosfamida , Interleucina-6 , Farmacología , Usos Terapéuticos , Leucopenia , Trombocitopenia
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA