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1.
Alexandria Journal of Pharmaceutical Sciences. 1994; 8 (2): 148-9
en Inglés | IMEMR | ID: emr-31607

RESUMEN

This study reported the preparation of some new bridgehead nitrogen compounds using the beta-keto ester and indane-1,3-dione with 3-amino- 1,2,4-triazole and aminobenzimidazole


Asunto(s)
Compuestos de Nitrógeno/farmacología , Análisis Espectral/métodos
2.
Alexandria Journal of Pharmaceutical Sciences. 1994; 8 (2): 150-3
en Inglés | IMEMR | ID: emr-31608

RESUMEN

The pyrazolo [1,5-a] pyrimidine derivatives IV and VI underwent pyrimidine ring opening, then recyclized when heated with aqueous alcoholic alkali solution to give the corresponding pyrazolo [3,4-b] pyridine V and VII, respectively. In a similar manner, the triazolo [4,3-a] pyrimidine VIII underwent recyclization to the corresponding triazolo [1,5-a] pyrimidine IX


Asunto(s)
Pirimidinas/síntesis química , Pirimidinas/análogos & derivados
3.
Alexandria Journal of Pharmaceutical Sciences. 1994; 8 (3): 173-174
en Inglés | IMEMR | ID: emr-31633

RESUMEN

The biindone I reacted with morpholine or piperidine and formaldehyde to give the corresponding Mannich bases IIa-b. Treatment of I with formaldehyde, and formaldehyde in AcOH, afforded II and IV, respectively. Compounds V and VI were prepared by treating I with benzaniline and isatinanil, respectively. Coupling of I with benzenediazonium chloride led to the formation of VII


Asunto(s)
Química , Aminas/química , Compuestos de Diazonio
4.
Alexandria Journal of Pharmaceutical Sciences. 1994; 8 (3): 187-191
en Inglés | IMEMR | ID: emr-31638

RESUMEN

In alcoholic methylamine solution, 2-alkylpyrimidines underwent rearrangement to 2-methylaminopyridines. Similarly, in alkaline medium, even a nonquaternized 2-methyl-5-nitropyrimidine formed 2-amino-5-nitropyridine


Asunto(s)
Química , Farmacocinética
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