Does intrauterine insemination in Saudi female cause production of antisperm antibodies?

To determine the possibility of inducing antisperm antibodies in patients undergoing intrauterine insemination with motile sperms from the husband. Clinico-immunological prospective study. King Abdulaziz University Hospital. Fifty patients undergoing Intrauterine Insemination [IUI], were tested for developing antisperm antibodies using agglutination test, complement mediated immobilization test, and immunoglobin specific indirect immunobead assay. Incidence and type of antisperms antibodies. Forty seven out of 50 patients remained negative for antisperm antibodies after 2-6 cycles of IUI. Detection of antisperm antibodies after IUI was evident in 3 patients [6 percent]. Intrauterine insemination does not appear to cause a significant or lasting immune response

use of ovarian KTP laser drilling in the treatment of anovulatroy infertility and polycystic ovarian disease

Determine the efficacy of unilateral laparoscopic ovarian drilling in the management of resistant ovarian syndrome. Design: A prospective randomized study of 20 women treated over a period of two years with follow-up till 8 months after the last woman was treated. Setting: Reproductive Endocrine Unit, King Abdulaziz University Hospital and Dr Soliman Fakeeh Hospital. Patients: 20 patients with refractory anovulatory infertility. All of these 20 women had been treated medically but without success. Intervention: Laparoscopic ovarian drilling by KTP/532 Laser. Main Outcome Measures: Rate of ovulation and endocrinal changes after ovarian drilling by KTP/532 laser. Unilateral ovarian drilling by KTP laser lead to ovulation from both ovaries. Seventy percent of the patients who had unilateral laser cauterisation had ovulation from both ovaries. In the responder group, there was a significant fall in LH concentration. The mechanism of action of KTP laser drilling of ovaries is by correcting the abnormal hormonal status. Unilateral ovarian drilling leads to bilateral ovarian activity

Fetal heart and vibroacoustic stimulation the first Saudi experience

The response of the term fetuses to the external sound stimulation had been already documented in the literature. This showed increase in the fetal heart rate [FHR] reactivity and Fetal Body Movements. However, the effect of this external sound stimulation on premature fetuses has not been fully documented. The aim of this study is to define the FHR changes after external vibration acoustic stimulus in a group of preterm healthy fetuses at 32 - 34 weeks. There was an immediate increase in the basal FHR in premature fetus at 32-34 weeks and significant increase in the mean duration of FHR acceleration. There was no significant change in the number of acceleration or fetal heart variability in these fetuses and no increase in the gross body fetal movements after vibroacoustic stimulation

Fetal macrosomia.what to do?

This is a two year retrospective review of 221 pregnancies that resulted in the delivery of an infant weighing 4000 gm or more [macrosomic babies]. Women delivering macrosomic fetuses were significantly older, of high parity, obese [> 90 Kg] and had higher frequency of postmaturity than the control. The macrosomic infant was more often male and had more birth trauma and shoulder dystocia but not to a statistically significant level. The method of delivery of a macrosomic baby should be individually considered as some women can achieve vaginal delivery of "very macrosomic baby" without significant increase in the maternal and perinatal mortality or morbidity, although in our series there was a relatively higher rate of delivery by caesarian section