Analysis of vaccination certificate inspection and supplementary immunization among children entering kindergarten and school in Chaoyang District, Beijing from 2014 to 2020 / 中国学校卫生

Objective@#To understand the situation relating to vaccination certificate inspection and supplementary immunization among children entering kindergarten and school in Chaoyang District.@*Methods@#The data on vaccination certificate inspection and supplementary immunization among children entering kindergarten and school in Chaoyang District from 2014 to 2020 were reviewed and statistically analyzed.@*Results@#From 2014 to 2020, a total of 5 886 kindergartens and primary and secondary schools in Chaoyang District inspected the vaccination certificates of children entering kindergarten and school, and the coverage rate of inspection was 100%. A total of 605 675 children were inspected, and the coverage rate of inspection was 100%. The average certificate holding rate of children was 99.35%. The certificate holding rate of children in each year was between 99.29% and 99.97%, the difference was statistically significant ( χ 2=3 389.80, P <0.01), and an overall increasing trend was observed. There were statistically significant differences in children s certificate holding rates among different institutions ( χ 2=1 276.81, P <0.01) and different household registrations ( χ 2=1 476.78, P <0.01). The certificate replenishment rate for children entering kindergarten and school was 100%. As part of the national immunization plan, eight types of vaccines have been supplemented with 71 875 doses in total, with an average supplement rate of 99.71%. The vaccine supplement rate has been increasing annually, and the difference was statistically significant ( χ 2=414.10, P <0.01). After 2017, the vaccine supplement rate reached 100%. In respect to the eight national immunization program vaccines, the number of replenishing doses has been decreasing annually. In the case of replenishing doses, the top three vaccines were MMR vaccine, MPSV vaccine and DT vaccine.@*Conclusion@#The work carried out as part of vaccination certificate inspection and supplementary immunization among children entering kindergarten and school in Chaoyang District has continued to improve. The children s certificate holding rate, the certificate replenishment rate, and the vaccine supplement rate are maintained at a high level.

B-mode ultrasound for defining planning target volume in intensity-modulated radiotherapy for prostate cancer / 南方医科大学学报

<p><b>OBJECTIVE</b>To define the planning target volume (PTV) margins in intensity-modulated radiotherapy (IMRT) for prostate cancer without imaging guidance using B-mode acquisition and targeting (BAT) ultrasound-based prostate localization.</p><p><b>METHODS</b>Ten patients with prostate cancer underwent BAT ultrasound alignment before each IMRT session. The set-up deviations, each consisting of isocenter displacements in 3 directions (anterior-posterior, right-left lateral, and superior-inferior), were recorded for a total of 225 times and analyzed with Kolmogorov-Smimov (K-S) method.</p><p><b>RESULTS</b>The isocenter shift in each direction, which represented an average from all the patients, was 3.56∓2.71 mm, 4.08∓3.99 mm, and 3.20∓2.92 mm in the lateral (RL), anteroposterior (AP), and superior-inferior (SI) dimensions, respectively, and the deviations in each direction conformed to a normal distribution (P=0.806, P=0.061, and P=0.106, respectively). In the absence of imaging guidance for IMRT for prostate cancer, the PTV margin should expand by 8.97 mm in the right, 1.87 mm in the left, 12.05 mm in the anterior, 3.91 mm in the posterior, 9.06 mm in the superior and 2.66 mm in the inferior to allow 95% isodose curve to cover 90% of the clinical target volume.</p><p><b>CONCLUSION</b>The ultrasound imagining guided localization, with simple operation, nonirradiation and small systemic error, can be real-time corrected.</p>

Determination of the repair half-time of human nasopharyngeal carcinoma cell lines CNE1, CNE2, HONE1 and C666-1 / 南方医科大学学报

<p><b>OBJECTIVE</b>To determine the repair half-time (T1/2), a speed parameter of sub-lethal damage repair (SLDR), of human nasopharyngeal carcinoma (NPC) cell lines CNE1, HONE1, C666-1 and CNE2.</p><p><b>METHODS</b>A total radiation dose of 8 Gy divided into 4+4 Gy was delivered to the cell lines at the interval of 0 s, 15 s, 30 s, 1 h, 2 h, 4 h or 6 h. The cell survival fractions were determined using the standard cell clonogenic assay. The curves of the changes in the surviving cell fraction after a total dose of 8 Gy, as a function of the interval between the two doses of 4 Gy, were fitted manually, and the T1/2 of each cell line was calculated according to the curves.</p><p><b>RESULTS</b>The T1/2 of CNE1, HONE1, C666-1 and CNE2 were 18 s, 22 s, 29 s and 27 s, respectively.</p><p><b>CONCLUSION</b>The speed of SLDR of NPC cells is quite rapid, indicating that the fraction delivery time longer than 20 s might decrease the effect of radiotherapy.</p>

The application of 64 multidetector CT angiography in the evaluation of carotid stenosis and followup of carotid endarterectomy and percutaneous transluminal stenting / 中华放射学杂志

Objective To evaluate the diagnostic value of 64 multidetector-row CT angiography for internal carotid artery(ICA)stenosis and the application in the follow-up of carotid endarterectomy and percutaneous transluminal stenting.Methods Forty transient ischemie attack(TIA)patients with interpretable CTA and DSA of the cervical carotid arteries were selected from May 2005 to December 2005. This yielded a total of 80 vessels.The CTA curved planar reformations(CPR)and DSA images referenced to the distal cervical internal carotid were graded by two senior neuroradiologists blindly,according to the North American Symptomatic Carotid Endarterectomy Trial(NASCET)guidelines.The paired-t test was used to verify the statistical significant difference between pre-operating and post-operating of carotid endarterectomy or percutaneous transluminal stenting in measuring the vascular diameter and area of cross section using CTA.Results When the 70% stenosis was used as the cut-off value,the seasitivity,specificity,negative predictive value,and the positive predicting value were 97%,95%,95%,and 98%,respectively.There was statistically significant difference in measuring the vascular diameter(P

Application of triple rule-out with 64-slice spiral CT in the diagnosis of acute chest pain / 中华放射学杂志

Objective To investigate the performance of triple rule-out with(M-slice spiral CT in the combined examination of pulmonary artery,thoracic aorta and coronary artery for patients with acute chest pain.Methods Seventy patients who presented with acute chest pain were included in the study.All of the patients underwent retrospective ECG-gated 64-slice computed tomography triple rule-out examination to evaluate the pulmonary arteries,thoracic aorta and coronary arteries.Multi-planar reconstruction(MPR), maximum intensity projection(MIP),curved-planar reconstruction(CPR)and volume rendering(VR) were used to display pulmonary arteries,thoracic aorta and coronary arteries.We evaluated the image quality of coronary artery and the enhancement of the pulmonary artery and thoracic aorta to estimate if the examination can fulfill the clinical demand for the differential diagnosis of acute chest pain.Results The mean scan time was(8.5?1.0)s,and the dose of contrast medium injected was 100 ml.There were 95.7%(67/70)of patients whose CT values detected in the pulmonary artery and thoracic aorta after enhancement were ≥200 HU.The image quality of 85.8%(720/839)coronary segments was classified as excellent,8.6%(72/839)as good,and 5.6%(47/839)as poor.There were 20 cases with coronary stenoses≥50%,2 cases with pulmonary embolism,and 2 cases with aortic dissection.Conclusion The triple ride-out examination with 64-slice spiral CT could depict pulmonary artery,thoracic aorta,and coronary artery in 8 s with good image quality.It has great potential in the etiological diagnosis for the patients with acute chest pain.

A study on the application of CT perfusion and CT angiography with 64-slice spiral CT in the evaluation of internal carotid artery and middle cerebral artery stenosis and occlusion / 中华放射学杂志

0.05),the MTT values were(5.2?1.1)and(10.9?2.6)s, respectively(t=7.24,P