RESUMEN
Circular RNA (circRNA),a class of non-coding RNA (ncRNA),widely exists in various kinds of cells. CircRNA is highly conserved in different species and can act as a miRNA sponge to regulate gene expression. More and more studies showed that circRNA plays an important role in pathogenesis and development of digestive system neoplasms, and can be used as a biomarker for diagnosis and prediction of prognosis. However,its function still needs further research to verify. This article reviewed the advances in study on role of circRNA in digestive system neoplasms.
RESUMEN
Circular RNA (circRNA),a class of non-coding RNA (ncRNA),widely exists in various kinds of cells. CircRNA is highly conserved in different species and can act as a miRNA sponge to regulate gene expression. More and more studies showed that circRNA plays an important role in pathogenesis and development of digestive system neoplasms, and can be used as a biomarker for diagnosis and prediction of prognosis. However,its function still needs further research to verify. This article reviewed the advances in study on role of circRNA in digestive system neoplasms.
RESUMEN
ItisacknowIedgedthatintestinaImicrobiotapIaysanimportantroIeinIifeprocess.IntestinaIdysbiosisis invoIved in the pathogenesis of many diseases reIated to aImost every system of the body. Probiotics and fecaI microbiota transpIantation,which can moduIate intestinaI microbiota without severe adverse effects,has become a hot topic for disease treatment. This articIe summarized the use of intestinaI microbiota moduIation for treatment of digestive system diseases.
RESUMEN
Objective To explore the therapeutic efficacy of nanometer high-frequency square pulse light technology targeting kidney cancer.Methods Fifty BALB/c nude mice were vaccinated with human ACHN cell line and randomly divided into 1 control group and 4 therapeutic groups.The 4 therapeutic groups were cured with high-frequency square pulse light and nanometer high-frequency square pulse light.The treatment cycle was 4 weeks.The tumor growth condition and tumor-repres-sion change were observed and compared.Results The tumor volumes of the control group in-creased obviously,whereas the tumor volumes of the therapeutic groups decreased obviously or in-creased gently.The mean tumor volume and the tumor growth curve of the therapeutic groups were significantly lower than those of the control group(P＜0.05),but there was no significant difference between the therapeutic efficacy of the kidney cancer using high-frequency square pulse light and nanometer high-frequency square pulse light(P＞0.05).Synteresis of kidney carcinogenesis experiments results indicated that using high-frequency square pulse light and nanometer high-frequency square Dulse light could prevent the production and development of the kidney cancer(P＜0.05),but the svnteresis efficacy of the 2 methods had no obvious difference(P＞0.05).Conclusion Using highfrequency square pulse light and nanometer high-frequency square pulse light can cure the kidney cancer and,to some extent,prevent the production and development of kidney cancer.