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1.
Indian J Physiol Pharmacol ; 1991 Oct; 35(4): 278-80
Artículo en Inglés | IMSEAR | ID: sea-107345

RESUMEN

Neem oil, an oil extracted from the seeds of Azadirachta indica has been found to act as a good spermicidal agent. Pre and post coital application of the oil intravaginally prevented pregnancy in rhesus monkey.


Asunto(s)
Animales , Peso Corporal , Moco del Cuello Uterino/química , Anticonceptivos Femeninos/farmacología , Femenino , Glicéridos/farmacología , Concentración de Iones de Hidrógeno , Macaca mulatta , Embarazo , Progesterona/sangre , Radioinmunoensayo , Terpenos/farmacología
2.
Indian J Physiol Pharmacol ; 1991 Jan; 35(1): 21-6
Artículo en Inglés | IMSEAR | ID: sea-106267

RESUMEN

Depot-medroxy progesterone acetate (DMPA) was jet deposited into the uterus/cervix of rats, rabbits and rhesus monkeys with the help of a modified jet injection apparatus. Since the drug was delivered under pressure, it was distributed deep into the muscular layers around the place of deposition. After one deposition the drug acted as an effective contraceptive for a period of three months. The merits of this delivery technique are discussed.


Asunto(s)
Animales , Cuello del Útero , Anticonceptivos Femeninos/administración & dosificación , Femenino , Hormona Folículo Estimulante/sangre , Inyecciones a Chorro , Hormona Luteinizante/sangre , Macaca mulatta , Masculino , Medroxiprogesterona/administración & dosificación , Acetato de Medroxiprogesterona , Embarazo , Progesterona/sangre , Conejos , Ratas
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