Peritoneal infection and bacteraemia following endoscopic injection sclerotherapy

Peritoneal infection and bacteraemia following endoscopic injection sclerotherapy [EIS] were studied in 30 patients presenting with liver cirrhosis, ascites and oesophageal haemorrhage. Blood and ascitic fluid samples were collected for cultures just before and 24 hours after EIS. They were cultivated both aerobically and anaerobically at 37degree. Eight patients [22%] developed bacteraemia while six other patients developed peritoneal infection [20%] following EIS. Higher rates of bacteraemia and peritoneal infection were found in patients with advanced liver disease. Staph aureus [4 cases], Strept viridans [2 cases], Staph. epidermidis [1 case] and C. haemolyticum [1 case] were isolated from cases with bacteraemia. While, E. coil [3 cases], klebsiella [2 cases] and Candida albicans [1 case] were isolated from ascitic fluid cultures. None of the patients with positive ascitic fluid cultures had any clinical evidence of peritoneal infection. Accordingly a high index of suspicion is important in order to diagnose cases with peritoneal infection following oesophageal endoscopic sclerotherapy even in absence of clinical evidence of infection with special emphasis on patients with grade [c] liver cirrhosis

Serum IgM and IgG levels in diabetics with nosocomial urinary tract infection

This study included 60 patients from Kasr EI-Eini Hospital suffering from nosocomial urinary tract infection [UTI], 30 of them are diabetics and 30 are non diabetics, and also 20 normal controls. Urine counts and cultures are done to isolate the causative organisms and serum IgM and IgG levels are determined [as a parameter of humoral immunity]. Results of this study revealed that E. coli was the predominant isolate in both diabetics [80%] and non diabetics [70%] followed by Klebsiella [20% in both groups] Pseudomonas aeruginosa was isolated only from non diabetic group [10%]. Both groups showed statistically siginificant increased levels of IgG and IgM when compared to the control group. However, no statistically significant difference was found when both diabetic and non diabetic groups are compared