1.
Braz. j. med. biol. res
;
23(12): 1233-5, 1990. ilus
Artículo
en Inglés
| LILACS
| ID: lil-103649
RESUMEN
Rabbit and, to a lesser extent, human immunoglobulins (IgGs) are cleaved by snake venoms. The snake venom proteases active on IgGs release fragments which behave on SDS-PAGE like Fab units similar to those release by the thiol-activated enzymes. However, in contrast to the cysteine proteases, the activity of snake venom proteases on IgGs is not only blocked by metal chelating agents but is also inhibited by thiol compounds. The snake enzymes active on IgG are metalloproteases
Asunto(s)
Conejos , Ratas , Animales , Humanos , Fragmentos Fab de Inmunoglobulinas/metabolismo , Inmunoglobulina G/metabolismo , Venenos de Serpiente/metabolismo , Electroforesis en Gel de Poliacrilamida , Péptido Hidrolasas/metabolismo , Venenos de Serpiente/enzimología
2.
Braz. j. med. biol. res
;
18(3): 337-40, 1985. ilus
Artículo
en Inglés
| LILACS
| ID: lil-27418