RESUMEN
During 2004 to 2009, 701 patients with diabetes were under community-hospital-based integrated management at Zhonghua and Xiagang community health-care service centers, Xiamen, Fujian.Changes of clinical indicators, life-style and frequency of checks for its complications in them were compared before and after the management. All clinical indicators decreased with length of management, with fasting blood glucose from ( 7. 6 ± 2. 3 ) mmol/L before management to ( 7. 3 ± 2. 0) mmol/L half a year after management, (7. 2 ± 2. 1 ) mmol/L one year after management, (6. 9 ± 1.7 ) mmol/L two years after management. Their life-style also improved significantly and frequency of checks for complications increased with: 54. 4% for retinopathy, 52. 5% for diabetic foot, and 51.8% for neuropathy after management (P ＜0. 05).
RESUMEN
Objective To investigate the role of insulin resistance in the pathogenesis of childhood benign acanthosis nigricans with obesity and the relationship between insulin resistance and insulin receptors.Methods Fasting plasma insulin and the amount of erythrocyte insulin receptors were determined among17children with benign acanthosis nigricans with obesity(CBANO),with16cases of simple adiposis and15healthy children as controls.Results The levels of plasma insulin were higher in CBANO than those in sim-ple adiposis and healthy controls;however,the amount of erythrocyte insulin receptors was lower in CBANO than that in simple adiposis and healthy controls.Conclusion Insulin resistance caused by diminished in-sulin receptors may play an important role in pathogenesis of CBANO.
RESUMEN
Objective To investigate the effect of potassium iodide on the incidence of sporotrichosis, and provide the theoretical basis for the prevention of sporotrichosis. Methods Experimental mice were divided into 4 groups, group 1～3 were fed with water containing different doses of potassium iodide, and no potassium iodide was given to the control group. After two weeks, the fungi were inoculated intraperitoneally to all the mice. In the third to the eighth weeks, the mice were sacrificed every week in batches. The infection, pathological changes and mycological findings of the mice were observed. Results The incidence rate of experimental sporotrichosis was significantly decreased in the mice (P
RESUMEN
The organisms in pathologic tissues of sporotrichosis were detected by ABC technique. Brown spores were found, some spores appeared to be round, or pearshaped,budding spores or asteriod hotlies were observed, and some spores were phagocytlzed by leukocytes and macrophages. The diameter of spores ranged from 2. spin to 10. 0um. The sensitivity of this method is 96. 2% and the specificity 100%. Examining one case takes about three hours. The method can be used for retrospective study, as well as rapid diagnosis of sporotrichosis.