Role of Nasal irrigation in treatment of acute sinusitis [comparative study between alkaline nasal wash and curcumin herbal extract]

Acute sinusitis treatment may be with medications such as antibiotics or in few cases surgery. Natural options are also available. The present study was done to evaluate the efficacy of curcumin herbal extract as nasal irrigation versus alkaline nasal wash as an adjuvant treatment of acute sinusitis. Ninety patients were enrolled in this study, suffering from acute sinusitis. Patients were taken from outpatient clinic of multicenters in Kingdom of Saudi-Arabia from Jan. to June 2009 their age ranged from 25-48 years [mean 32 +/- 2 years]. There were 60 males and 30 females. Patients were divided into 3 equal groups. The first group was treated with curcumin nasal spray 3m1 in each nostril of concentration 1mg/ml twice daily for 10 days. Another group was treated by standerized alkaline nasal wash for 10 days [3 times daily] Both groups also were given the ordinary treatment in the form of antibiotics, analgesic and mucolytics. The third group was given the ordinary treatment only for 10 days .The results of the present study showed a considerable difference between nasal curcumin treatment and other groups. Nasal curcumin was superior to alkaline nasal wash in reducing or eliminating symptoms of acute sinusitis also endoscopically the curcumin group showed a considerable improving for both nasal mucosa and clearance of nasal discharge. Curcumin herbal treatment could help in treatment of acute sinusitis by its anti inflamatory, anti microbial effects

Modified buccal myomucosal pedicled flap in repair of wide defect cleft palate.

This study was carried out at the Pediatric Surgery Unit, Faculty of Medicine, Al-Azhar University from January 1999 to May 2002 to present an experience in the treatment of 40 children aging from 1-2 years old with wide defect cleft palate. Twenty children were exposed to buccal myomucosal pedicled flap to repair the defect [group A] and the other twenty children were exposed to modified two- flap palatoplasty technique [group B]. In group A, one child developed small palatal fistula, one developed wide palatal fistula and the other eighteen children healed without complications. In group B, two boys developed partial disruption, two developed palatal fistula of the wide type and the other sixteen boys healed without complications. In group A, in the eighteen healed children, by follow up, only one child developed nasal regurge and nasal tone in phonation, but the other seventeen children were completely normal. In group B, from the sixteen healed children, two children developed nasal regurge and nasal tone in phonation, but the remaining fourteen children were completely normal