The diagnosis of coronoid impingement using computed tomography / 대한구강악안면방사선학회지

Coronoid impingement can cause limitation of mouth opening. In many cases, it appears to be related to the coronoid hyperplasia. We present a case of mouth opening limitation caused by coronoid impingement on the posterior surface of the zygomatic bone without coronoid hyperplasia. The bony changes in coronoid and zygoma including surface irregularity and discontinuity of the cortex and sclerotic change of inner medullary space were noted on computed tomography (CT) scans in different level of axial planes. Through another CT scans in open mouth position could demonstrate that those bony changes were caused by the contact of both surfaces against each other. In case coronoid impingement is suspected of the many possible causes, the open mouth CT scans will be needed to reveal the direct impingement of coronoid on zygoma even without coronoid hyperplasia.

Relationship between trabecular strength and three-dimensional architecture in the pig mandible using microcomputed tomography / 대한구강악안면방사선학회지

PURPOSE: To investigate the relationship between three-dimensional (3D) bone imaging parameters and trabecular strength in the mandible. MATERIALS AND METHODS: Bone specimens were obtained from the mandibles of five male pigs weighing around 110 kg each. Of those, 43 samples were selected for 3D analysis and measured by micro-computed tomography. The five morphometric parameters were trabecular thickness (Tb.Th), bone specific surface (BS/BV), percent bone volume (BV/TV), structure model index (SMI) and degree of anisotropy (DA). Through destructive mechanical testing, strength parameters were obtained. RESULTS: BV/TV, SMI, BS/BV, and Tb.Th showed significant correlations with strength parameters. DA did not show any correlation with the other parameters. In multiple linear regression analysis, BV/TV alone explained 43% of the variance in Young's modulus. By stepwise inclusion of SMI, the variance in the Young's modulus was better explained up to 52%. CONCLUSIONS: Predicting trabecular strength in the mandible through architectural analysis would be possible. Further study is needed to establish the tendency and variety of trabecular architecture and strength according to the locations within the mandible.

The influence of X ray beam angulation on the fractal analysis of trabecular architecture in human dry mandible using standardized tile counting method / 대한구강악안면방사선학회지

PURPOSE: The purpose of this study is to examine the effects of X-ray beam angulation on the fractal dimension of trabecular bone structure of human dry mandible using the tile counting method. MATERIALS AND METHODS: We divided 5 human dry mandibles into an angle and a molar groups depending on the regions and deciding the region of interest (ROI). When contrasted with the ROI, the inferior cortex was appointed to be low and the lines perpendicular to the buccal cortex were appointed to be the standard angle. Direct digital intraoral radiographs were obtained from 9 different projection angles. We analyzed statistically the fractal dimension using the tile counting method. RESULTS: There was a statistically significant difference in the fractal dimension of the regions and the mandibles, but there was no statistically significant difference in the fractal dimension according to the X-ray beam angulation. CONCLUSION: There is no statistically significant effect of the angle of the projection on the fractal dimension of trabecular bone structure of a human dry mandible according to the tile counting method.

Irradiation Effect On The Apoptosis Induction In The Human Cancer Cell Lines And The Gingival Fibroblast / 대한구강악안면방사선학회지

The radiation-induced apoptosis was studied for two human cancer cell lines (KB cells, RPMI 2650 cells) and the human gingival fibroblast cell line (HGF-1 cells). The single irradiation of 2, 10, 20Gy was done with 241.5 cGy/min dose rate using the 137Cs MK cell irradiator. The cell were stained with propidium iodide and examined under the fluoro-microscope and assayed with the flow cytometry a day after irradiation. Also, the LDH assay was done to determine the amount of necrotic cells. The obtained results were as follows : 1. On the fluoro-microscope, many fragmented nuclei were detected in the KB, RPMI 2650, and HGF-1 cells after irradiation. 2. On the DNA content histogram obtained from the flow cytometry, the percentages of the pre-G1 peak of the control and 2, 10 and 20Gy irradiation group were 4.5, 55.0, 52.3, and 66.6% on KB cells, 2.7, 3.3, 31.8, and 32.6% on RPMI 2650 cells and 2.8, 21.8, 30.4, and 40.2% on HGF-1 cells respectively. 3. The number of G1-stage cells was abruptly decreased after 2Gy irradiation on KB cells and 10Gy irradiation on RPMI 2650 cells, But there was a slight decrease without regard to irradiation dose on HGF-1 cells. 4. There was no significantly different absorbance in extracellular LDH assay along the experimental cell lines.