Expression of the biological marker PCNA in breast carcinoma

The study determined the expression of the biological marker PCNA in invasive breast carcinoma patients treated at Oncology Hospital and HCMC Medical and Pharmaceutical University Hospital from January 2003 to January 2004. The results found out the correlation of the marker with the basic prognostic factors such as: age of patients, histopathological features, histological grade, and lymph node metastases. Among 371 specimens of invasive breast carcinoma which were stained with immunohistochemical technique, there were 96.2% specimens have had the overexpression of PCNA in the cancer cells. However, there was not relation between the overexpression of PCNA and the basic prognostic factors, therefore, it is not necessary to find out the expression of PCNA in all cases of invasive breast carcinoma

Ulcer gastric and Helicobacter pylori infection

Study on 335 cases underwent endoscopic biopsies. The results showed that: The rate of Helicobacter pylori (HP) infection in gastric ulcer patients that had clinical symptoms were 63%, highest in group of 31 to 50 years old. Inflammatory and ulcer lesions were in antropyloric area, and the rate of HP (+) was highest in this area. In comparison with endoscopic diagnosis, the highest ratio of HP was in gastric ulcer accompany with duodenal bulb ulcer, and lowest rate was in acute inflammation. There was no significant difference in infected frequency between male and female. However, moderate and severe infections (Hp2+, Hp3+) in men were more common than those in women

Pathological and endoscopic features of rectocolic lesions

Study 480 cases of rectocolon endoscopic biopsies, to compare the clinical features with the features and microscopic diagnosis. Results: the patients between 50 and 70 years old had the rate of highest catch a diseases and malignant lesions. There was no difference in the cancer ratio between male and female. The percentages of 4 groups included: malignant tumors, inflammatory lesions, polyps and benign tumors, were about 48%, 30%, 13.75% and 6.87%. Malignant tumors occur mainly in the rectum (65.36%) and in the sigmoid colon (9.95%). Most of malignant tumors in the colon and rectum (96%) were adenocarcinoma. The true-positive percentage of endoscopic diagnosis (confronted with microscopic finding) in the cancer group was 70.56%