hydatid cyst found in an uncommon site coincidentally

Echinococcosis or hydatid cyst disease is a common parasitic disease that is known to affects both humans and animals. Echinococcosis manifests as a cyst formation, is caused by E. Granulosis [unilocular cystic] and E. Alveolaris [multilocular cystic] and is an important health problem in poorly developed countries. In this paper, we report and discuss a rare case of primary hydatid disease presenting as uterus leiomyoma at 33-weeks of gestation. Hydatid cysts in the genital tract are rare and gynaecologists should be cognisant of the possibility of hydatid cysts when a mass is found in the uterus

Extra-adrenal myelolipoma: a case report and review of the literature

Myelolipoma of the adrenal gland is a rare, benign and biochemically inactive tumor comprising mature fat and hematopoietic elements. Most of these lesions are discovered incidentally. The vast majority occurs within the adrenal glands, but extra-adrenal myelolipomas have also been reported. The typical extra-adrenal myelolipoma is a solitary, well-defined mass with in abdomen. We present a 70 year old male who came to us with pain of 5 months duration. Abdominal ultrasound examination showed a 12 x 8.5cm hyperechoic heterogenous semi-solid mass localized in the right-side. Histological examination of the mass revealed the features of extra-adrenal myelolipoma

Examination of the distribution of mast cells in the nasal mucosa of patients with seasonal allergic rhinitis

It is known that mast cells play an important role in pathogenesis of allergic rhinitis. In this study, we investigated the distribution of mast cells in the nasal mucosa of patients with seasonal allergic rhinitis during the pollen-season. This study was carried out at the Faculty of Medicine, Dicle University, Turkey, during the grass-pollen season between, March and July in 2002. Twenty patients with seasonal allergic rhinitis [12 females and 8 males] and 20 healthy [10 females and 10 males] non-allergic controls were examined for the distribution and abundance of mast cells in nasal biopsies. Biopsies were performed in all patients and controls, once during natural provocation in the spring and were taken from the lower edge of the inferior turbinate using a forceps. The samples of nasal mucosa were fixed in 10% neutral buffered formaline, stained with 0.5% aqueous toluidine blue and hematoxylin and eosin were examined under a light microscope. Mast cells were observed in the nasal mucosa obtained from 12 patients [60%] and 5 patients [25%] controls cases [p=0.025]. It was found out that intrapitelial mast cells are present in nasal mucosa samples of patients with SAR [seasonal allergic rhinitis] but not in the epithelium of non-allergic controls. The number of submucosal mast cells has considerably increased in the nasal mucosa samples of patients with SAR. Besides this, these cells are determined in great amounts in non-allergic individuals

Strong Association of HMB - 45 expression with renal angiomyolipoma

Angiomyolipoma [AML] is a benign neoplasm consisting of varying mixtures of smooth muscle, blood vessels and fat. Although, most of these tumors are easy to recognize, some may pose a diagnostic dilemma due to unusual histologic features. Recently, it was suggested that melanosome-associated protein [HMB-45] immunoreactivity may be used for diagnostic confirmation of several neoplasm. The aim of this study is to analyze the diagnostic efficacy of HMB-45 in patients with AML. This study was carried out at the Faculty of Medicine, Department of Pathology, Dicle University, Diyarbakir, Turkey, during the period January 2000 to September 2003. HMB-45 immunoreactivity was analyzed in 6 patients with AML and in 34 patients with other renal and retroperitoneal pathologies, including 10 nephrectomized patients for non-neoplastic reasons by means of immunohistochemistry. Patients with AML were positive for HMB-45. Whereas, HMB-45 immunoreactivity was negative in all of the histologic specimens from the patients with renal cell carcinoma, retroperitoneal sarcomas, Wilms' tumor, lipoma, leiomyoma, and nephrectomized kidneys of non-neoplastic reason. The association of AML with HMB-45 immunoreactivity was highly significant [p<0.001]. Our findings suggest that HMB-45 may not be a melanocyte-restricted marker, and can be useful in differential diagnosis between AML and other tumors seen in kidney and retroperitoneal region