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Mem. Inst. Oswaldo Cruz ; 96(7): 1001-1003, Oct. 2001. ilus
Artículo en Inglés | LILACS | ID: lil-298898

RESUMEN

Inocula, varying from 15 to 1,000 embryonated Capillaria hepatica eggs, were administered to young adult rats by gastric tube, in an attempt to investigate the influence of worm load in the production of septal fibrosis of the liver. Low doses of 15, 30 or 50 eggs were sufficient to produce septal fibrosis, but it appeared with variable degrees of intensity and always with focal distribution. Septal fibrosis became diffuse, progressive with time, and already well developed 40 days after infection, when 100 eggs or more were administered. However, higher inocula (200, 500 and 1,000 eggs) did not intensify septal fibrosis, although the number of parasitic focal lesions proportionally augmented


Asunto(s)
Animales , Masculino , Ratas , Femenino , Capillaria/patogenicidad , Infecciones por Enoplida/complicaciones , Cirrosis Hepática Experimental/etiología , Parasitosis Hepáticas/etiología , Modelos Animales de Enfermedad , Cirrosis Hepática Experimental/parasitología , Cirrosis Hepática Experimental/patología , Parasitosis Hepáticas/parasitología , Parasitosis Hepáticas/patología , Ratas Wistar
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