1.
Indian J Biochem Biophys
;
1990 Aug; 27(4): 240-4
Artículo
en Inglés
| IMSEAR
| ID: sea-26377
RESUMEN
Binding of chlorpromazine (CPZ), a widely used antidepressant tranquilizer, with hemoglobin has been studied by equilibrium dialysis method. r/Cf versus r plot was typically concave downwards revealing the positive cooperative nature of binding. Binding parameters, namely the affinity constant (K) and the degree of cooperativity (nH) were determined from the Hill plot. Oxygen was found to be released gradually from hemoglobin with gradual addition of CPZ, the extent of oxygen release depending on the stoichiometric ratio of CPZ: hemoglobin (D/P).
Asunto(s)
Sitios de Unión , Clorpromazina/metabolismo , Hemoglobinas/efectos de los fármacos , Humanos , Cinética , Oxígeno/metabolismo
2.
Indian Heart J
;
1986 Mar-Apr; 38(2): 155-7
Artículo
en Inglés
| IMSEAR
| ID: sea-4728
Asunto(s)
Adulto , Cardiomegalia/diagnóstico , Diagnóstico Diferencial , Femenino , Atrios Cardíacos , Humanos
3.
Indian Heart J
;
1983 Nov-Dec; 35(6): 366-8
Artículo
en Inglés
| IMSEAR
| ID: sea-3730