Effect of anesthesia and surgery on thyroid function of geriatric patients.

This work was carried out on 15 old female patient undergoing surgery under general anesthesia. The thyroid function [fT4, TSH] and hemodynamic [MAP and HR] responses to anesthesia and surgery were evaluated. Pre-operative estimation of fT4 and TSH revealed a low normal level of fT4 [12.7 pmo/L] and marginal elevation of TSH [1.84 IU/L], i.e. subclinical hypothyroidism. During surgery fT4 and TSH were insignificant decreased, i.e. the normal hemodynamic response to surgical stress is abolished in these patients. Thyroid function should be carefully evaluated in female geriatric patients before any surgical procedure

Effect of some recent analgesics on labour pain and materno-fetal blood cases and pH

This studs attempts to determine the analgesic property of nalbuphine hydrochloride, pentazocine lactate and butorphanol tartarate during labour, and their potential effects on materno-fetal blood gases and pit. The analgesic efficacy of the tested drugs was assessed by Steinhouse scoring systern [1964]. Butorphanol analgesia was superior to either nalbuphine or pentazocine in relieving labour pains. The studied analgesics caused significant maternal respiratory acidosis and fetal metabolic acidosis. These acidotic changes were more marked in the pentazocine, moderate in the nalbupitine and minimal in the butorphanol group