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Int. braz. j. urol ; 44(5): 892-899, Sept.-Oct. 2018. tab, graf
Artículo en Inglés | LILACS | ID: biblio-975631

RESUMEN

ABSTRACT Purpose: The purpose of our study was to evaluate the clinical impact of 68Ga-PSMA PET / CT in the setting of biochemical recurrence of prostate cancer. Materials and Methods: We retrospectively evaluated 125 prostate cancer patients submitted to the 68Ga-PSMA PET / CT due to biochemical recurrence. The parameters age, Gleason score, PSA levels, and the highest SUVmax were correlated to potential treatment changes. The highest SUVmax values were correlated with age and Gleason score. The median follow-up time was 24 months. Results: 68Ga-PSMA PET / CT led to a treatment change in 66 / 104 (63.4%) patients (twenty-one patients were lost to follow-up). There was a significant change of treatment plan in patients with a higher Gleason score (P = 0.0233), higher SUVmax (p = 0.0306) and higher PSA levels (P < 0.0001; median PSA = 2.55 ng / mL). Conclusion: 68Ga-PSMA PET / CT in prostate cancer patients with biochemical recurrence has a high impact in patient management.


Asunto(s)
Humanos , Masculino , Adulto , Anciano , Anciano de 80 o más Años , Oligopéptidos , Neoplasias de la Próstata/sangre , Neoplasias de la Próstata/diagnóstico por imagen , Ácido Edético/análogos & derivados , Antígeno Prostático Específico/sangre , Tomografía Computarizada por Tomografía de Emisión de Positrones/métodos , Recurrencia Local de Neoplasia/diagnóstico por imagen , Neoplasias de la Próstata/terapia , Estudios Retrospectivos , Estudios de Seguimiento , Sensibilidad y Especificidad , Clasificación del Tumor , Persona de Mediana Edad , Recurrencia Local de Neoplasia/terapia
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