Carcinoma of the pancreas in childhood: a case report of long term survival.

Cancer of the pancreas in the pediatric age group is very rare. The incidence of pain and jaundice of clinical pictures is found less than in the adult. A case of a 13-year-old girl who was successfully treated by radical pancreaticoduodenectomy (Whipple's operation) with long term survival is reported. The literatures were reviewed the revealing only hope for long term survival is by radical resection which was proved by many authors. Infants and children tolerate radical resection of the pancreas somewhat better than adults with a lower mortality rate and providing long term survival.

Lack of interferon induction in man by two rabies tissue culture vaccines.

Both neutralising antibody and interferon play a part in protection of animals against death from rabies virus infection. Interferon induction was therefore sought in 53 volunteers within 24 hours of receiving human diploid cell strain vaccine or fetal bovine kidney cell vaccine given either intramuscularly or intradermally. Repeat observations were made in 18 subjects following a second dose of vaccine seven days later. No interferon was detected in any sample tested although no subject had any detectable rabies neutralising antibody on day 0. The sensitivity of the interferon assay, and comparison with other studies are discussed. An interferon inducer suitable for human use should be sought as an alternative to, or a replacement for, passive rabies immunization.