Fixed Turbinate Resection in the System of Nasal Endoscopic Surgery in Patients with Refractory Nasal Polyps Sinusitis Curative Effect Analysis / 医学研究杂志

Objective To study the fixed nasal endoscopic surgery combined with turbinate resection system of refractory nasal polyps sinusitis patients curative effect.Methods From December 2014 to June 2016,92 patients in our hospital for treatment of refractory nasal polyps sinusitis which were randomly divided into observation group and control group,with 46 cases in each.The patients in the observation group were treated with modified nasal endoscopic surgery combined with turbinate resection treatment system,and control group patients underwent conventional surgical treatment.The effects of two groups were compared.Results Total efficiency of the observation group was significantly higher than that of the control group.Symptoms after treatment in the two groups,SNOT-20 scores were significantly lower thon these in the treatment before,and symptoms after the treatment group,SNOT-20 scores were significantly lower than these of control group.The complication rate and recurrence rate in the observation group were significantly lower than the control group.The differences were statistically significant (P ＜ 0.05).Conclusion The correction of nasal endoscopic surgery combined with turbinate resection system in the treatment of refractory nasal polyps sinusitis effect significantly,can significantly reduce the pain of patients,and promote an early recovery of patients.

Expression and correlation of cyclooxygenase-2 and vascular endothelial growth factor in nasopharyngeal carcinoma- / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To evaluate the Expression and correlation of cyclooxygenase-2 (COX-2) and vascular endothelial growth factor receptor (VEGF) in nasopharyngeal carcinoma.@*METHOD@#In this study, expression levels of COX-2, VEGF were examined in 58 patients with nasopharyngeal carcinoma and 38 patients with inflammation in nasopharyngeal mucosa by immunohistochemistry method.@*RESULT@#The expression of COX-2, VEGF were higher in nasopharyngeal carcinoma than those in nasopharyngeal mucosa (P < 0.05), and they had some correlation with the invasion and lymphatic metastasis and with the clinical stage of nasopharyngeal carcinoma (P < 0.05). The expression of COX-2 was positively correlated with that of VEGF (P < 0.05).@*CONCLUSION@#The coexpression of COX-2 and VEGF may play animportant role in the carcinogenesis and development of nasopharyngeal carcinoma, and they may prom (see text) lymph node metastasis of nasopharyngeal carcinoma.

The expression and relationship of cyclooxygenase-2 and latent membrane protein-1 in nasopharyngeal carcinoma / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To discuss the expression and correlation of COX2 and LMP1 in NPC.@*METHOD@#Fifty-three nasopharyngeal biopsy specimens of NPC patients who had been diagnosed definitely with pathology in our department from 2000 to 2005, and 8 nasopharyngeal biopsy specimens of chronic nasopharyngitis patients were collected. The expression of COX2, LMP1 were detected with streptavidin peroxidase immunohistochemistry staining. All the datas were analyzed with SPSS 12.0.@*RESULT@#The positive expression rate of COX2 was 71.70% (38/53), and that of LMP1 was 66.04% (35/53) of Nasopharyngeal carcinoma tissue. The higher expression rate was detected in neck lymph nodes metastasis group of nasopharyngeal carcinoma (P0.05). The expression of COX2 and LMP1 showed positive correlation (gamma = 0.797, P<0.01).@*CONCLUSION@#COX2 and LMP1 were highly expressed in nasopharyngeal carcinoma cells. The expressions of COX2 and LMP1 was significantly associated with neck lymph nodes metastasis, and was none-significant relation with age, gender, clinical stage and pathological classification. The expression of LMP1 showed a significant positive correlation with that of COX2. LMP1 could enhance NPC neck lymph nodes metastasis by up-regulating the expression of COX2.

Clinical study of nasal endoscopic surgery on 30 cases of noninvasive fungal stnusitis / 中国基层医药

Objective To study the effect of nasal endoscopic surgery on the noninvasive iungal sinusitis. Methods 30 cases of noninvasive fungal sinusitis were treated with nasal endoscopic surgery. Results In the follow up of 6～36 months, all cases were cured and no one had a recurrence. Conclusion Nasal endoscopic surgery can de- crease the damage of the operation and shorten the time of treatment,and can reduce the recurrence of this disease.