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Objective To investigate the influence of start time of continuous renal replacement therapy (CRRT) on the survivay and renal function recovery of patients with severe acute kidney injury (AKI)Methods Two hundred cases of severe AKI patients in the Traffic Hospital of Shandong Province from January 2011 to January 2014 were selected and divide into groups A of 1 phase,group B of 2 phase and group C of 3phase based on the CRRT starting time.The survivary and renal function recovery of 3 groups patients were compared.Results After treatment,the recovery rate of renal function,survival rate and mortality of patients in group A were 91.04％,92.5％ and 36.2％,significantly higher than that of group B(52.11％,73.6％ and 7.5％) and group C (29.03％,36.2％ and 63.8％),the differences were statistically significant (x2 =6.266,16.143,16.143;P＜0.05);and the recovery rate of renal function and survival rate of group A was higher than of group B and C (P＜0.05);and renal function index of groupA,B,C all significantly improved than before treatment,there were statistically significant differences (P＜ O.05).Conclusion Early CRRT treatment can significantly improve the survival rate of patients with SCKI,which would be good for patients to recover renal function.
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Objective To measure the fractional anisotropy(FA) values in the language function areas(Broca area,Wernicke area and arcuate fasciculus)by diffusion tensor imaging(DTI),discussing the pathological characteristics in cerebral palsy children with language development delay.Methods DTI was performed in twenty-seven cerebral palsy children with language development delay(observation group) and 20 children with febrile seizures(control group) by Philips 3.0T MRI scanner.The FA values of Broca area,Wernicke area and arcuate fasciculus were measured at Philips Workstation.Results The FA values of control group in the left Broca area,Wernicke area and arcuate fasciculusis were higher than those of the right side,and the difference was statistically significant (all P ＜ 0.05).The FA value of observation group in the left Broca area was lower than that of the right side,and the difference was statistically significant (P ＜ 0.05);the FA values of observation group in the left Wernick area and arcuate fasciculusis were higher than those of the right side,but the difference was not statistically significance (all P ＞ 0.05).The FA values in the bilateral Broca area and arcuate fasciculusis of observation group were lower than those of the control group,the difference was statistically significant (P ＜ 0.05),those in the bilateral Wernick area were also lower than the control group,but the difference was not statistically significant (P ＞ 0.05).Conclusions The main pathogenesis for language development delay in cerebral palsy children was extensive damage in language functional areas,and Broca area and arcuate fasciculus were markedly impaired than Wernick area.