Early detection of pregnancy following ovulation induction and intra-uterine insemination in luteal phase defect infertile patients

Ovarian stimulation and intra-uterine insemination were induced in patients with luteal phase defect [LPD]. The corpus luteum function was supported by human chorionic gonadotropin. The early pregnancy was detected 14 days after insemination. The concentration of progestrone and beta-HCG was significantly higher in the luteal support group than the non-luteal support group. The concentration of luteinizing hormone, prolactin and estradiol was significantly higher in the pregnant group compared to non-pregnant group. The pregnancy rate in the support group was also significantly higher than the non-support group [64% versus 36% respectively]. The early detection of pregnancy in severe LPD patients followed with luteal support therapy was found in this study to have clinical significance in pregnancy maintenance

Pathogenesis of vaginal discharge

A total of 56 adult female attending the outpatient Gynaecology Clinic of Medical City Teaching Hospital of Baghdad were selected for the purpose of this study. Forty of these patients had variable degress of vaginal discharge, while the rest were asymptomatic with normal speculum examination. Pathogenic and normal flora in both groups of patients were indentified employing culture, wet-preparation and gram stained films of the high vaginal swabs taken from all patients under study. The pathogenic organisms isolated from vaginal discharge patients included Candida albicans [15%], Trichomonas vaginals [10%], Gardenerella vaginals10%],Beta hemolytic stepococci group B [10%], and Gram-negative coliforms 35% [including E. coli [25%], Klebsiella species [17.5%] and proteus [2.5%]; while in 27% of cases no pathogenic agent could be isolated in spite of evidence of infection, such cases were considered to be chlamydial, mycoplasmal or viral in nature. Other microorganisms isolated and considered as normal flora included staphylococcus albus, lactobacilli, beta hemolytic streptococci group D, non- hemolytic streptococci, yeasts other than candida albicans, staphylococcus aureus and bacillus species