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Journal of Forensic Medicine ; (6): 413-416, 2006.
Artículo en Chino | WPRIM | ID: wpr-983236

RESUMEN

OBJECTIVE@#To investigate the structural characteristics of the cerebral small vessels with an unknown type of pathological lesion (UTPL).@*METHODS@#Contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with UTPL were studied by Congo red staining, immunohistochemical staining and computer image analysis.@*RESULTS@#The low expression levels of alpha-actin and collagen IV (P<0.05) were observed in tunica media of the vessels with UTPL, and no positive expression of beta-amyloid (P>0.05) was observed in these vessel walls. The expressions of proteins mentioned above in UTPL were different from those of cerebral amyloid angiopathy(CAA) and hyaline arteriolosclerosis.@*CONCLUSION@#UTPL was different from CAA or hyaline arteriolosclerosis in pathologic feature.


Asunto(s)
Humanos , Actinas/metabolismo , Péptidos beta-Amiloides/metabolismo , Autopsia , Vasos Sanguíneos/ultraestructura , Encéfalo/patología , Angiopatía Amiloide Cerebral/patología , Colágeno Tipo IV/metabolismo , Procesamiento de Imagen Asistido por Computador , Inmunohistoquímica , Coloración y Etiquetado , Hemorragia Subaracnoidea/patología
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