Cytokines of human myocardial fibroklasts induced by Coxsackievirus B3 / 中国免疫学杂志

Objective:Infection with CVB3 may cause severe cardiovascular disease. The mechanisms are not clear,cytokines may have immportant functions,but which kind of cells are they come from is not known well, myocardial fibroklasts is the main cells.The cytokines were determined after infection with CVB3.Methods:IL 6, IL 8, IL 1?, IL 1? and TNF ? in the supernate were measured with ELISA. Results:IL 6 and IL 8 increased significantly after CVB3 infection( P