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No abstract available.
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Herpes Simple , Huésped Inmunocomprometido , Terapia de Inmunosupresión , SimplexvirusRESUMEN
Leptospirosis has a wide spectrum of nonspecific clinical manifestations ranging from mild diseaseto multiorgan failure with variable cutaneous manifestations. Disseminated herpes simplex virusinfection usually occurs in the setting of immunosuppression. Both these infections are rare infectivecauses of fulminant hepatitis. Herein, we report a case of fatal leptospirosis and disseminated herpessimplex virus coinfection, in the hopes that this report will increase awareness among health careproviders for relevant investigation and prompt management.
RESUMEN
BACKGROUND: There have been several studies about herpes zoster in the Korean dermatological literatures. However, there are few studies reported on disseminated herpes zoster. OBJECTIVE: The aim of this study is to determine the epidemiology and clinical features of the disseminated herpes zoster as compared with herpes zoster. METHODS: The authors retrospectively reviewed the medical records on 14 cases of disseminated herpes zoster and 402 cases of herpes zoster at the Department of Dermatology Busan Paik hospital during the 3 years from 2010 to 2012, and if necessary, telephone interviews were executed. RESULTS: The rate of new disseminated herpes zoster outpatients at our dermatology clinic was 0.11% with the mean age of 67.7 years and the males to females ratio was 2.5. The most frequent involved dermatome was the lumbar (42.9%) area. The rate of patients with underlying diseases or immunosuppression, the rates of postherpetic neuralgia and the frequency of narcotic analgesics uses were significantly higher in disseminated herpes zoster as compared with herpes zoster. The patient treatment satisfaction was significantly higher in herpes zoster as compared with disseminated herpes zoster. CONCLUSION: These results demonstrated that the disseminated herpes zoster is associated with higher rates of underlying diseases, immunosuppression, frequent incidences of postherpetic neuralgia, more uses of narcotic analgesics and lower patient treatment satisfactions as compared with herpes zoster.
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Femenino , Humanos , Masculino , Dermatología , Herpes Zóster , Terapia de Inmunosupresión , Incidencia , Entrevistas como Asunto , Registros Médicos , Narcóticos , Neuralgia Posherpética , Pacientes Ambulatorios , Estudios RetrospectivosRESUMEN
Herpes zoster is a cutaneous infection that is characterized by an acute vesicobullous rash with ipsilateral one or two dermatomal distribution and painful allodynia, while predominantly being found in the elderly. Extensive cutaneous dissemination has been reported in immune-compromised patients, such as those who suffer from HIV infections, cancer, chemotherapy, and corticosteroid therapy patients. However, we report a case of disseminated herpes zoster infection in an immuno-competent elderly individual.
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Anciano , Humanos , Exantema , Herpes Zóster , Herpes Zóster Ótico , Infecciones por VIH , Hiperalgesia , Inmunidad CelularRESUMEN
BACKGROUND: Although there were many clinical studies of herpes zoster, researches on the clinical manifestations of disseminated herpes zoster are few in Korean dermatologic literatures. OBJECTIVE: The aim of this study was to describe their clinical characteristics of disseminated herpes zoster, and compare them to that of previously reported literatures. METHODS: We enrolled 16 patients diagnosed as disseminated herpes zoster at our institution from 2008 to 2012 in this study. We assessed with age, sex, underlying diseases, primary dermatome, interval to dissemination, prodromal symptoms, range of lesions, and complications of disseminated herpes zoster on the basis of medical records. RESULTS: The mean age of subjects was 66.25 and the ratio of males to females was 2.2 : 1. 68.75% of all subjects had various underlying diseases, and hypertension was the most common disease. The most frequent primary dermatome was thoracic, and the average interval of dissemination was 2.19 days. Among 14 subjects with prodromal symptoms, 13 patients had pain, and 7 patients had rare symptoms including general weakness, myalgia, and fever, etc. Skin involvement was moderate to severe in 87.5%, and postherpetic neuralgia was the most common complication. CONCLUSION: The patients of disseminated herpes zoster were more common in men, and had a broader range of lesions and higher incidence of underlying disease. In addition, they had rare general symptoms, and more complications as meningitis and neurogenic bladder. However, statistical comparisons are difficult due to small sample size, and therefore, additional studies targeting patients from multiple institutions will be required.
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Femenino , Humanos , Masculino , Fiebre , Herpes Zóster , Hipertensión , Incidencia , Meningitis , Neuralgia Posherpética , Síntomas Prodrómicos , Tamaño de la Muestra , Piel , Vejiga Urinaria NeurogénicaRESUMEN
Herpes zoster is characterized by unilateral grouped vesicles along the distribution of a single dermatome. Disseminated herpes zoster usually is defined as a generalized eruption of more than 20 extra-dermatomal vesicles occurring within a week of the onset of classic dermatomal herpes zoster. It occurs chiefly in old or debilitated individuals, and especially in patients with underlying malignancy, immunosuppressive therapy, or human immunodeficiency virus (HIV) infection. A 51-year-old man presented with segmental grouped vesicles on the left upper trunk and arm, and a varicella-like eruption over the entire body. Tzanck smear preparation and punch biopsy done on the vesicles of the trunk indicated a herpetic infection. Later, he was found to be HIV-positive. We report a rare case of HIV infection initially presenting with disseminated herpes zoster.