RESUMEN
As one of the high frequent malignancies in China,liver cancer has different disease background and clinicalmanagement modalities compared with that in foreigncountries. In recent years,China has made great progress inthe diagnosis and treatment of liver cancer. In the earlydiagnosis,a series of accomplishments have been achieved inliquid biopsy techniques represented by circulating micro RNA(mi RNA), circulating tumor cell(CTC),and circulating tumorDNA(ctDNA),which remarkably promoted the early diagnosis of liver cancer. In the surgical treatment,through continuousexploration of novel surgical methods,surgical indications andanti-recurrence and-metastasis strategies,patients get moresurgical opportunities,lower risks of metastasis and relapseand significantly prolonged overall survival. In addition,clinical research of liver cancer has received unprecedentedattention. The conclusions of some clinical trials have servedas important evidence to direct the development of guidelines,and to choose appropriate treatment strategies for patients inChina,which is more in line with the characteristics of livercancer in China.
RESUMEN
To evaluate the clinical applicability and application of Guidelines for Diagnosis and Treatment of Common Diseases of Gynecology in Traditional Chinese Medicine, 11 diseases from Guidelines for Diagnosis and Treatment of Common Diseases of Gynecology in Traditional Chinese Medicine were evaluated by methods of questionnaire and prospective case study at 16 construction units for traditional Chinese medicine standards research and extension. Results showed that 361 clinical doctors accepted the applicability survey of guidelines, and 87.26% of them were more familiar to the guideline and 25.21% of them used the guideline. In syndrome differentiation and treatment related contents, rationality of prescription medication and syndrome classification was higher, accounted for 91.69% and 86.98% respectively, but the rationality of recuperation prevention was lower, accounted for 44.6%. 75.62% clinical doctors believed that the Guidelines for Diagnosis and Treatment of Common Diseases of Gynecology in Traditional Chinese Medicine was applicable. The application of the guidelines is evaluated by prospective observation of 2 935 cases. The higher compliance between the guideline and clinical practice was present in TCM (traditional Chinese medicine) disease diagnosis and WM (western medicine) disease diagnosis, accounted for 98.30% and 94.11% respectively. The lower compliance was present in recuperation prevention, accounted for 59.39%. The safety and economy of the guideline was higher, accounting for 95.64%, 94.75%, respectively. The comprehensive evaluation results showed that the rate of the overall treatment effect with technical level, satisfaction degree or applicability in clinical practice which were 7-9 points is 77.38%, 74.00%, 76.90% respectively. This guideline has a high clinical compliance and can be used as a standard for common diseases of gynecology, but there are also some conditions with poor applicability, which does not conform to the actual situation, and needs to be further revised.