RESUMEN
Objective To investigate the influence of start time of continuous renal replacement therapy (CRRT) on the survivay and renal function recovery of patients with severe acute kidney injury (AKI)Methods Two hundred cases of severe AKI patients in the Traffic Hospital of Shandong Province from January 2011 to January 2014 were selected and divide into groups A of 1 phase,group B of 2 phase and group C of 3phase based on the CRRT starting time.The survivary and renal function recovery of 3 groups patients were compared.Results After treatment,the recovery rate of renal function,survival rate and mortality of patients in group A were 91.04％,92.5％ and 36.2％,significantly higher than that of group B(52.11％,73.6％ and 7.5％) and group C (29.03％,36.2％ and 63.8％),the differences were statistically significant (x2 =6.266,16.143,16.143;P＜0.05);and the recovery rate of renal function and survival rate of group A was higher than of group B and C (P＜0.05);and renal function index of groupA,B,C all significantly improved than before treatment,there were statistically significant differences (P＜ O.05).Conclusion Early CRRT treatment can significantly improve the survival rate of patients with SCKI,which would be good for patients to recover renal function.
RESUMEN
The optimal intensity of continuous renal-replacement therapy in severe acute kidney injury is uncertain,but the establishment of optimal dose of CRRT is the key to successful treatment.In this paper,the basis for setting dose of CRRT starts analysis of the current CRRT dose and the efficacy of the evidence in evidence-based medicine and problems and presents the need of severe acute renal injury for greater CRRT dose.The purpose is to guide clinicians to set an optimal CRRT dose and improve the prognosis of severe acute renal injury.