RESUMEN
Objective:To analyze the passive smoking exposure and its influencing factors in non-smokers aged≥18 in Tianjin.Methods:This was a cross-sectional study. Based on the 2018 Tianjin Adults Noncommunicable Disease and Nutrition Surveillance, non-smokers aged≥18 years old at 7 surveillance sites were selected as the research objects, taking 2018 population data of Tianjin as the standard population, the sample data were weighted to analyze the general demographic characteristics, the level of passive smoking exposure, the cognition of tobacco harm, and the influencing factors of passive smoking exposure. Pearson χ 2 test was used to compare the rate between groups, and the influencing factors were analyzed by unconditional logistic regression. Results:After weighted, the passive smoking exposure rate was 51.5%, among non-current smokers, the awareness rates of smoking related lung cancer and passive smoking related adult lung cancer were 83.3% and 80.0%, respectively. The awareness rates of smoking related stroke and passive smoking related heart disease in adults were 61.4% and 66.4%, respectively. The awareness rate that smoking related stroke was higher in the non-passive smoking exposed group than in the secondhand smoke exposed group (62.7% vs 60.3%, P<0.05). There was no statistical difference in the awareness rate of smoking related heart attacks and lung cancer as well as passive smoking related adult heart disease, adult lung cancer, and lung disease in children between the passive smoking exposed group and the non-passive smoking exposed group (all P>0.05). The awareness rate of smoking related three diseases (stroke, heart attack and lung cancer) was 57.9% and the awareness rate of passive smoking related three diseases (heart disease in adults, lung cancer and lung disease in children) was 64.9% in non-current smokers. Among men, undergraduate or above was a protective factor for second-hand smoke exposure. Heads, clerical and related personnel of state organs, party and mass organizations, enterprises and public institutions were risk factors for secondhand smoke exposure. Among women, age ≥60 years and high education were protective factors for secondhand smoke exposure. Conclusions:Non smokers aged 18 and above in Tianjin have a higher level of passive smoking exposure, and the awareness rate of tobacco exposure related cardiovascular diseases is low. In future, the health education of relevant knowledge should be strengthened.
RESUMEN
Background: Tobacco usage and alcohol consumption is a serious health issue to the society for ages. The consumption of alcohol and tobacco usage leads to medical and societal issues. An assessment of the pattern of tobacco usage and alcohol consumption in adult population is important to estimate the burden, and the risk factors associated with the same on the rural communities. There is a strong impact on the prevalence of NCDs by reduction in the usage of tobacco and alcohol products in the forthcoming decades. Methods: A community based cross-sectional study was conducted in the rural field practice area of a medical college, using pre-validated, semi-structured questionnaire amongst 275 study participants a rural area. The adults aged 18 years and above who were currently using tobacco products and consuming alcohol were selected by simple random sampling using the tobacco assessment and AUDIT questionnaire for alcohol consumption. Results: The results showed a significant association between all the socio-demographic variables (except for gender) in the usage of tobacco products; the study found higher literacy levels in using the products more frequently. The age distribution, family arrangement and socio-economic status were associated with alcohol consumption as well. In the multivariate regression the socio-economic class were associated with alcohol consumption. Conclusions: The interventions should be targeted at the family and community level. There is a need for health education programs and de-addiction camps.
RESUMEN
Mishri is a form of smokeless tobacco used as a dentifrice in rural areas of central India. Mishri is applied to teeth and gums to clean the oral cavity. Mishri use has ill effects on oral health and periodontal tissues. The present study assessed the ill effect of mishri application periodontal tissues, and its correlation to the duration of use. A total of 300 subjects who used mishri as a dentifrice were considered. The enrolled subjects were categorized into three subgroups depending on the years of mishri usage. Age, gender, education level, socioeconomic status (SES), and body mass index (BMI), were recorded. Periodontal clinical parameters i.e. plaque index, gingival index, clinical attachment loss, and probing pocket depth were assessed. The data were statistically correlated with the duration of mishri usage with the Chi-square test and Analysis of variance. Out of the 300 subjects, 162 (54%) were males and 138 (46%) were females. SES and BMI had no association with mishri use but education level played a significant role in the avoidance of mishri use (P - 0.041). All the periodontal clinical parameters deteriorated with the duration of mishri use (P - 0.0001). It was concluded that mishri use was common in both genders. There was a deterioration of periodontal health and the progressive destruction of periodontal tissues with years of mishri use. The Dentist and community health workers should educate about the ill effects of tobacco use and mishri, as a dentifrice among the rural population.
RESUMEN
Context: Smokeless tobacco (SLT) has been consumed in India since times immemorial. It is the need of an hour to emphasise about awareness and harmful effects of SLT in relation to periodontium. Aim: The aim of the study was to access the prevalence of periodontitis and its association with SLT amongst the adult population of Greater Noida, India. Settings and Design: Hospital?based study and cross?sectional design. Methods and Material: This cross?sectional study included 512 SLT subjects between the ages of 18 and 79 years. The study was carried out from December 2019 to January 2022. A self?designed questionnaire was used for recording demographic details, forms of SLT, frequency, duration of use, and sites of retention of SLT products. The clinical periodontal parameters such as periodontal pocket depth (PPD) and clinical attachment level (CAL) were recorded in a given point of time. Statistical Analysis Used: Chi?square test and logistic regression analysis. Results: The prevalence of periodontitis among SLT was 81.6% with the highest occurrence of Stage III Periodontitis (35.4%). The use of SLT for ?10 years [odds ratio (OR) = 3.05, 95% confidence interval (CI) 1.86–6.27] showed threefold the risk for periodontitis compared to others who consumed SLT for 4–5 years. Gutkha consumers [OR = 2.56 (95% CI = 0.75–3.48)] were 2.56 times more prone to have periodontitis as compared to other forms of SLT. Conclusions: Periodontitis is positively associated with SLT use. Awareness, timely intervention, and periodic screening in the SLT users will help to prevent the progression of periodontitis.
RESUMEN
Introduction: Myocardial infarction (MI) is one of the leading causes of mortality in India. The associated risk factors vary with respect to geographical and cultural difference in patients of MI. Objective: To study the association between known risk factors and MI in patients visiting tertiary rural health care center. The study design was Unmatched Case Control type. Patients of age 18 or above diagnosedMethod: of AMI were included as cases. Patients of age 18 or above without prior history of heart disease were included as controls. Pregnant women and patients with coexisting cardiogenic shock, any significant chronic medical illness was excluded. The history of hypertension, Diabetes, family history of CHD, stress in past 1 year, history of alcohol intake, History of tobacco addiction, type of activity at work were recorded. The comparison of case and controls were done using Chi square test, Fisher's Exact Test and Odds ratio, wherever applicable. A one sided “p” value of <0.05 was considered significant. Of the 230 studyn Results: participants included in the study, 100(43.5 %) were cases and 130 (56.5%) were Control, respectively. Except for history of stress, there was no statistical difference between number of cases and controls. Conclusion: The known risk factors of MI were not found associated with the disease. There is a need for conduct of study with larger sample size for confirmation of the study results.
RESUMEN
Background & objectives: Contrary to overall declining trend in smokeless tobacco (SLT) use in India, an increase is observed in north-east (NE) India. This study examined the predictors of daily SLT use by gender and assessed the demographic and socio-economic characteristics that contribute to gender differences in SLT use in NE India. Methods: Data collected from 15,259 and 13,574 adults in the two rounds of Global Tobacco Adult Survey 1 and 2 for NE India during 2009-2010 and 2016-2017 were analyzed. Relative change, multivariable binary logistic regression and Blinder-Oaxaca decomposition analysis were used for analysis. Results: The findings suggest that among women in NE India, the daily SLT use significantly increased by 58 per cent between 2009-2010 to 2016-2017. Women residing in Nagaland, Manipur, Mizoram and Tripura were 3.5 and 2.5 times, respectively more likely to be daily SLT users compared to those in Assam. While age, education and wealth were the significant predictors of SLT use in both women and men, increased odds of SLT use were observed with women’s type of occupation and the State of residence. The majority of the gender differences in daily SLT use was explained by differences in work status (44%), age (26%), education (14%) and wealth status (9%) between men and women. Interpretation & conclusions: Increasing prevalence of SLT use amongst women in the NE States necessitates integration of gender-specific messages on harmful effects of SLT in the ongoing tobacco control programmes and development of culturally appropriate community-based interventions for cessation of SLT use.
RESUMEN
Abstract The aim of the present case-control observational study was to evaluate the peri-implant clinicoradiographic status among betel-quid chewers and controls. Self-reported betel-quid chewers and controls were included. Participants were categorized into 3 groups: Group-1: Individuals chewing betel-quid with tobacco; Group-2: Individuals chewing betel-quid without tobacco; and Group-3: Controls (individuals not using tobacco in any form). Demographic data was collected using a questionnaire. Periodontal and peri-implant clinicoradiologic parameters (plaque and gingival indices [PI and GI], probing depth [PD] and crestal bone loss/marginal bone loss [CBL/MBL]) were assessed. Clinical attachment loss (AL) around teeth was also assessed. Group comparisons were done using the one-way analysis of variance and Bonferroni Post-hoc adjustment tests. Correlation of periodontal and peri-implant inflammatory parameters with the duration of betel-quid chewing habit and duration of placement in the mouth were assessed using logistic regression analysis. P<0.05 was considered statistically significant. Thirty, 30 and 30 patients were included in groups 1, 2 and 3, respectively. Full-mouth PI (P<0.01), GI (P<0.01), clinical AL (P<0.01), PD (P<0.01) and mesial and distal MBL (P<0.01) were higher in groups 1 and 2 than Group-3. Peri-implant mPI (P<0.01), mGI (P<0.01), PD (P<0.01) and MBL/CBL (P<0.01) were significantly higher in groups 1 and 2 than Group-3 with no significant difference in groups 1 and 2. Betel-quid chewing habit either with or without tobacco is a risk-factor of peri-implant soft-tissue inflammation and CBL.
Resumo O objetivo do presente estudo observacional de casos-controles foi avaliar o estado clínico-radiográfico periimplantar dos usuários de bétele. Foram incluídos usuários que relataram utlizar a substância bétele como tabaco de mascar. Os participantes foram categorizados em 3 grupos: Grupo-1: Indivíduos que mascam bétele com tabaco; Grupo-2: Indivíduos que mascam bétele sem tabaco; e Grupo-3: Controle (indivíduos que não usam tabaco sob qualquer forma). Os dados demográficos foram recolhidos utilizando um questionário. Foram avaliados parâmetros clínico-radiográfico e periimplantares (índices placa e gengivais [IP e IG], profundidade de sondagem [PS] e perda de crista óssea/ perda óssea marginal [PCO/POM]). Também foi avaliada a perda inserção clínica (IC) em torno dos dentes. As comparações de grupo foram feitas utilizando a análise de variância unidireccional e os testes de ajustamento post-hoc de Bonferroni. A correlação dos parâmetros inflamatórios periodontais e periimplantares com a duração do hábito de mastigação da bétele e duração da colocação na boca foi avaliada utilizando a análise de regressão logística. P<0,05 foi considerado estatisticamente significativo. Foram utilizados 30 pacientes em cada grupo. O IP de boca inteira (P<0,01), IG (P<0,01), IC clínica (P<0,01), PS (P<0,01) e POM mesial e distal (P<0,01) foram mais elevados nos grupos 1 e 2 do que no grupo 3. O mPI peri-implantar (P<0,01), '(P<0,01), PD (P<0,01) e POM/PCO (P<0,01) foram significativamente mais elevados nos grupos 1 e 2 do que no grupo 3, sem diferença significativa nos grupos 1 e 2. O hábito de mastigar a substância bétele com ou sem tabaco é um fator de risco de inflamação dos tecidos moles periimplantares e PCO.
RESUMEN
Background: India Global Youth Tobacco Survey 2019 observed that 8.5% of the young age group (13-15 years) consume tobacco (9.6 % are boys and 7.4 % are girls). No interventional studies among adolescents were conducted before the initiation of the SLT use. Aims & Objectives: To estimate the prevalence of consumption of tobacco and non-tobacco products and to provide school based interventions to bring behavioral changes. Materials and Methods: An interventional study was carried out in Primary Schools. For estimation of the prevalence of tobacco and non tobacco use all the students of 1st to 5th while for the interventions, 4th and 5th standard were selected. Baseline data and change in the behavior at the end of one year was collected. FGD with key informants were also conducted. Descriptive Statistics was conducted. Results: The prevalence of smokeless tobacco consumption and non-tobacco product was found to be 1.3% and 36.5% respectively. After intervention 40.5% students had quit non tobacco products. Findings of FGD suggested that children should not be sent to purchase tobacco products on behalf of their parents. Conclusion: School based intervention and sensitization of the field workers along with knowing their perceptions for the predictors of consumption could be useful.
RESUMEN
Background:Ischemic heart diseases are the leading cause of death due to non-communicable diseases in India. Tobacco consumption is well proven risk factor for ischemic heart disease. Tobacco chewing is a very common practice done in Gujarat as well as other regions of India. Nicotine is the active ingredient in tobacco which causes alteration in lipid profile over long term consumption. According to “global adult tobacco survey (2016-2017)” over 21.4% of Indian adults consume smokeless/chewable tobacco. Present study was conducted to compare the lipid profile of non-tobacco consumers vs. chronic smokeless/chewable tobacco consumers.Material And Methods:The study was conducted after taking approval of Institutional Ethics Committee. A total of 100 selected study participants (non-obese male without any history of cardiovascular diseases and diabetes and not on any lipid altering medications) were divided in to case and control arm based on the history of consumption of CSLT(chronic smokeless tobacco)for 8 years or not. After overnight fasting,blood samples of both group individuals were taken for estimation of lipid profile. Details of lipid profile along with other demographic data were recorded in predesigned case record form. Result:A significant increase in lipid profile parameters such as TC, LDL, and TG were seen in chronic tobacco chewers compared to control group. Mean total cholesterol (TC), low density lipoprotein(LDL)and serum triglycerides levels in CSLT consumers were 222 mg/dl, 148 mg/dl and 171 mg/dl respectively. These parameters were higher in CSLT consumers as compared to control group by 68mg/dl (TC), 53 mg/dl (LDL) and 66 mg/dl (TG).Conclusion:Chr onic tobacco chewing was found to be associated with alteration in all the lipid profile parameters. Altered lipid profile is the proven risk for cardiovascular ailments. Hence ahypothesis can be generated from the study that CSLT consumption is the responsible factor for cardiovascular diseases. This can be tested further on large scale studies along with differences in the type of CSLT consumption and development of cardiovascular diseases can be evaluated.
RESUMEN
Background: Though there is a lot of literature available about presence of carcinogenic chemicals in these products, there is lack of information regarding the microbial composition of these products. Aim & Objective: The study was conducted with the objective of assessing microbial composition of smokeless tobacco products and factors associated with higher colony count. Methodology: This cross sectional study included a total of 43 samples obtained from four districts of Karnataka namely Udupi, Bengaluru, Bidar and Belagavi. Microbial populations were assessed using quantitative aerobic culture and colony forming units per gram was reported for each sample. The data was entered into excel and analysed using Statistical Package for Social Sciences version 16.0. Results have been expressed as frequencies and percentages. Univarate analysis was done to study association between background characteristics and higher colony counts. Results: All except three samples showed bacterial contamination. Two samples showed pathogenic bacterial growth, while the other 38 samples had non-pathogenic bacteria. There was no association between background characteristics and colony counts. Conclusions: Microbial contamination of smokeless tobacco products is common. There is a need to further investigate various factors associated with microbial contamination so that necessary interventions can be implemented.
RESUMEN
ABSTRACT: Despite the reported effects of smokeless tobacco (ST) on the periodontium and high prevalence of ST use in rural populations and in males studies on this specific topic are limited. The purpose of this cross-sectional investigation was to measure lipid peroxidation (as an end product of oxidative stress) end product i.e. Malondialdehyde (MDA) in saliva of patients with gingivitis, chronic periodontitis and to assess the influence of smokeless tobacco on Salivary Malondialdehyde (S-MDA). Total 30 patients with gingivitis, 30 with chronic periodontitis and 30 Smokeless Tobacco Chewers with Chronic Periodontitis and 30 periodontally healthy subjects were included in the study. Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PD), and Clinical Attachment Loss (CAL) were recorded followed by stimulated Saliva sample collection. Salivary MDA Levels were assessed by UV Spectrophotometry. There was a statistically significant increase in the salivary MDA levels in gingivitis, chronic periodontitis and in smokeless tobacco chewers with chronic periodontitis when compared with healthy group. Higher salivary MDA levels in gingivitis group, chronic periodontitis, and smokeless tobacco chewers with chronic periodontitis reflects increasedoxygen radical activity during periodontal inflammation.
RESUMEN: A pesar de los efectos reportados del tabaco sin humo (TS) sobre el periodonto y la alta prevalencia del uso de TS en poblaciones rurales y en hombres, los estudios sobre este tema específico son limitados. El propósito de esta investigación transversal fue medir el producto final de la peroxidación lipídica (como producto final del estrés oxidativo), es decir, malondialdehído (MDA) en la saliva de pacientes con gingivitis, periodontitis crónica y evaluar la influencia del tabaco sin humo en el malondialdehído salival (S-MDA). Se incluyeron en el estudio un total de 30 pacientes con gingivitis, 30 con periodontitis crónica y 30 masticadores de tabaco sin humo con periodontitis crónica y 30 sujetos periodontalmente sanos. Se registraron el índice de placa (PI), el índice gingival (GI), la profundidad de la bolsa de sondeo (PD) y la pérdida de adherencia clínica (CAL), seguidos de la recogida de muestras de saliva estimuladas. Los niveles de MDA en saliva se evaluaron mediante espectrofotometría UV. Hubo un aumento estadísticamente significativo en los niveles de MDA en saliva en gingivitis, periodontitis crónica y en masticadores de tabaco sin humo con periodontitis crónica en comparación con el grupo sano. Los niveles más altos de MDA en saliva en el grupo de gingivitis, periodontitis crónica y masticadores de tabaco sin humo con periodontitis crónica reflejan un aumento de la actividad de los radicales de oxígeno durante la inflamación periodontal.
Asunto(s)
Humanos , Periodontitis Crónica/inducido químicamente , Uso de Tabaco , Peroxidación de Lípido , Malondialdehído/análisisRESUMEN
ABSTRACT Objective: To evaluate the effects of commonly used smokeless tobacco forms on oral health at habitual placement sites of smokeless tobacco compared to non-placement sites among the North Indian population. Material and Methods: This cross-sectional study was conducted among 542 individuals using smokeless tobacco recruited from the outpatient wing of the Dental College. Subjects completed a questionnaire and received an oral examination. Periodontal pocket depth, gingival index, plaque index, gingival recession, and oral mucosal changes were assessed. Kendal's Tau test, paired t-test, and chi-square test were carried out to compare different variables among placement and non-placement sites. Results: Most of the subjects were male, reporting an average of 11.26 years of SLT use. Clinical inflammation of gingiva was significantly greater (p=0.01) at placement-sites (1.64 ± 0.53) of SLT in comparison to non-placement-sites (1.40 ± 0.41). The difference in the GR and PPD at placement and non-placement-sites was also statistically significant with p=0.002 and p=0.001, respectively. Clinically, the majority of subjects had mucosal changes at the placement sites, and a statistically significant association (p=0.034) was observed between the duration of the use of smokeless tobacco and the mucosal changes. Conclusion: Smokeless tobacco use predisposes to increased risk of periodontal diseases and oral mucosal changes at the placement sites in an individual due to the local irritant effect.
Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Periodontitis/patología , Salud Bucal/educación , Tabaco sin Humo/toxicidad , India/epidemiología , Mucosa Bucal/lesiones , Distribución de Chi-Cuadrado , Epidemiología Descriptiva , Estudios Transversales , Encuestas y CuestionariosRESUMEN
Background: Tobacco can be consumed as cigarettes and also as smokeless tobacco. Smokeless tobacco is a harmful tobacco product that contains over 3,000 chemicals, 7 including 28 known carcinogens (cancer-causing agents). Various forms of smokeless tobacco (mainly snuff and chewing tobacco) cause an immediate increase in heart rate and blood pressure. However, the relationship between smokeless tobacco uses on blood pressure remains unknown, especially in tertiary level hospitals. Our aim is to find out the smokeless tobacco use influence on cardiovascular parameters, for instance, pulse rate and blood pressure. Methods: This cross-sectional study was carried out to assess cardiovascular changes among adult male smokeless tobacco (ST) users. For this purpose, 50 male respondents were selected. The participants were selected from the medicine outpatient department of Great Eastern Medical School and Hospital, Srikakulam, Andhra Pradesh. Pulse rate and blood pressure were measured and ST uses behavior was assessed using self-reports. Statistical analysis was done by SPSS20. Results: In this study, the mean (±SD) of pulse rate was 83.2±12.3 beats/min. The mean (±SD) of systolic blood pressure was 158.72±24.84 mm of Hg and the mean (±SD) of diastolic blood pressure was 98.78±9.87 mm of Hg in smokeless tobacco users. Conclusion: Mean systolic and diastolic blood pressures were higher in smokeless tobacco users in the tertiary level hospital. However, the mean pulse rate was within the normal range.
RESUMEN
Background: Tobacco practice in relation with oral diseases is a foremost cause for the global oral disease burden and is accountable for up to 50% of all periodontitis cases among adults. The present cross-sectional study was undertaken to evaluate the local effects of various types of smokeless tobacco on periodontal health in tobacco pouch keratosis (TPK) patients in Mangalore city in the state of Karnataka. Materials and Methods: A total of 345 TPK patients were evaluated of which all were smokeless tobacco users. All the patients were clinically examined for different clinical periodontal parameters such as stains, gingival recession (GR), periodontal pocket, furcation involvement, and mobility and local effects of various types of smokeless tobacco on periodontal health in TPK sites were recorded. Results: The prevalence of GR was of 87.5%. Haathichaap was the most common smokeless tobacco used (35.9%) closely followed by nonpackaged type (loose tobacco) (19.4%). This was followed by Madhu (14.2%). Likewise, periodontal parameters were observed more in these patients in decreasing order. Conclusion: The results of the present study agree strongly with other smokeless tobacco user studies in terms of the strong association between GR and smokeless tobacco placement. The present cross-sectional study indicates that TPK lesions are positively associated with periodontal diseases. It is important to raise awareness of both oral cancer and periodontal risks and inform about its possible health consequences thereby working towards an improvement of oral and general health and related quality of life in these patients
RESUMEN
Background: This study aimed at assessing prevailing pattern and risk factors of tobacco consumption among health care workers of tertiary care centre, in Faridabad.Methods: A cross-sectional approach was used. A sample of 306 participants included housekeeping and nursing orderly. Participants were interviewed during their lunch time. Semi structured questionnaire was used for data collection.Results: The overall prevalence of tobacco use was found to be 42.8% (n=306), of which (30.7%) prevalence among housekeeping’s compared to nursing orderlies (12.7%). The consumption of smokeless tobacco was higher among housekeeping staff. Khaini (45%) was the main consumption type, followed by hookah (21%) and cigarettes (19.5%) among the current tobacco user (n=133). The consumption of tobacco was found to be associated with gender (male), education, and nature of job (designation) at the hospital setting.Conclusions: Tobacco use is very common in hospital staff in Faridabad as reflected by results of our study. We should build on success encountered in banning smoking in educational institutions and healthcare facilities. This is important for their health and also overall health of patients also as they can influence the behaviour of people that surrounds them.
RESUMEN
BACKGROUND@#Tobacco consumption causes almost 638,000 premature deaths per year in India. This study sought to examine the prevalence and determinants of tobacco use among men in India.@*METHODS@#We analyzed data from the fourth round of the National Family Health Survey in India. These nationally representative cross-sectional sample data were collected from January 20, 2015, to December 4, 2016. A total of 112,122 men aged 15-54 years were included in this study. Primary outcomes were tobacco use categorized into smoking, smokeless, any tobacco, and both smoked and smokeless tobacco use. Complex survey design and sampling weights were applied in both the descriptive analyses and logistic regression models. We present the findings using odds ratios.@*RESULTS@#The prevalence of tobacco use among men in India for the studied period was 45.5% (95% CI 44.9-46.1), smoking was 24.6% (95% CI 24.1-25.1), smokeless tobacco use was 29.1% (95% CI 28.6-29.6), and both smoked and smokeless tobacco use was 8.4% (95% CI 8.1-8.7). The prevalence of tobacco use among men was higher among the elderly, separated/divorced/widowed individuals, those with lower education and wealth status, alcohol consumers, manual workers, and residents of the northeast region. Multivariate analysis showed that age, lower education, occupation, region, alcohol consumption, separated/divorced/widowed status, and economic status were substantially associated with tobacco use among Indian men.@*CONCLUSIONS@#Innovative and cost-effective strategies targeting high-risk groups are crucial to curbing the tobacco epidemic in India. Anti-smoking campaigns should also focus on mitigating alcohol abuse. Reducing tobacco marketing and implementing formal education about the dangers of tobacco use, progressive taxing, packaging, and labeling of tobacco products and price strategies should be harmonized in legal provisions.
Asunto(s)
Adolescente , Adulto , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven , India/epidemiología , Prevalencia , Factores Socioeconómicos , Uso de Tabaco/epidemiologíaRESUMEN
Abstract Objective This study aimed to investigate the effects of Maras powder (a type of smokeless tobacco obtained from Nicotiana rustica Linn and mixed with the ashes of wood, especially from oak, walnut or grapevine) on the microRNA (miRNA) deregulation of oral mucosa, and it compares these effects with those of smoking. Methodology Oral mucosal samples were collected from 74 patients, consisting of 16 nonusers, 26 smokers, and 32 Maras powder users. Genes associated with oral cancer were selected and 90 microRNAs targeting these genes were identified. MicroRNA were isolated and purified using the microRNA isolation kit. MicroRNA were expressed using Fluidigm RT-PCR. Results A positive correlation between the duration of Maras powder use with miR-31 expression levels, and a negative correlation between the Maras powder chewing time and miR-372 expression levels was found. In addition, there is a negative correlation between the amount of Maras powder consumed and expression levels of miR-375, miR-378a, miR-145, and miR-10b; moreover, another negative correlation is observed between the number of cigarettes consumed and the expression levels of miR-23a, miR-23b, miR-203a, miR-200b, and miR-375. However, miR-200b and miR-92a levels were downregulated significantly more in Maras powder users when compared with smokers and nonusers (p<0.05). Conclusion The results show both chewing Maras powder and smoking have an effect on deregulation of miR-200b and miR-92a expressions. This leads to the belief that assessing the expression of these two miRNAs is a promising noninvasive method of analysis, especially in mutagen exposures. Finally, large-scale and high-throughput studies may help to identify an extensive miRNA expression profile associated with tobacco use and improve the understanding of oral malignancies.
Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Tabaco sin Humo/efectos adversos , MicroARNs/efectos de los fármacos , Mucosa Bucal/efectos de los fármacos , Polvos , Factores de Tiempo , Neoplasias de la Boca/genética , Regulación hacia Abajo , Expresión Génica , Estudios Transversales , Factores de Riesgo , Análisis de Varianza , MicroARNs/análisis , Reacción en Cadena en Tiempo Real de la PolimerasaRESUMEN
Background: Tobacco imposes a colossal burden of disease and death leading to catastrophic health, social, economic, and environmental effects. “Tobacco” kills both men and women but sex-specific differences exist. Traditional forms of tobacco like dentifrice or tobacco tooth powder and betel quid, tobacco and lime mixture are commonly used and also, the new products use is increasing not only among men but even among children, teenagers, women of reproductive age. This study was done to know the patterns and other correlates of tobacco use among the rural women in the reproductive age group.Methods: A community based cross sectional study, conducted from January 2011 to December 2011 among 1200 rural women aged between 15 years to 49 years residing in primary health centre, Vantmuri area, Belgaum, Karnataka, India. Statistical analysis was done using rates, ratios and chi-square tests.Results: Tobacco consumption was seen in 9.7% of the study participants. A very high percentage of 79 (67.5%) had more than 10 years of exposure to tobacco amongst the users. Dentifrice was the most common form of tobacco used (85.5%) followed by 32 (27.4%) plain tobacco consumption. However, 49 (4.1%) consumed multiple forms of tobacco, most common being dentifrice along with plain tobacco or paan with beetelquid or used snuff.Conclusions: The distribution of tobacco consumption is likely to maintain, and perhaps increase, the current considerable socioeconomic differentials in health in India. Dual users are at much higher health risks than those who consume the individual tobacco product. It also emphasizes the variations in patterns of using tobacco among rural women. There is a need for periodical surveys using more consistent definitions of tobacco use and eliciting information on different types of tobacco consumed.
RESUMEN
Background: Substance abuse is a serious problem because it is engulfing the younger generation with serious health, social and economic concern. This study was conducted to determine the prevalence of substance abuse among male adolescents and study the habit pattern of substance abusers.Methods: A cross sectional study was conducted among 776 male adolescents residing in urban and rural field practice areas under the department of Community Medicine, through randomly selected house to house visit. Data regarding the current use of alcohol and tobacco was collected in a predesigned and pretested proforma by oral questionnaire method.Results: The prevalence of substance abuse among male adolescents was found to be 22.8% and majority of them used some form of smokeless tobacco, followed by smoking tobacco. Consumption of alcohol or tobacco by adolescents is significantly associated with alcohol or tobacco consumption by their family members.Conclusions: Prevalence of substance abuse was high among the male adolescents and they should be motivated through IEC to give up the habit.
RESUMEN
Background: Concerned over increasing cases of mouth cancer in the state, the Jammu and Kashmir Government hasbanned the smokeless tobacco (ST) products like gutkha and also increased the taxes in other tobacco-related products.Despite legislation, the effectiveness of this step is a matter of concern. The gutka users are able to get their regular supplyand shopkeepers are still seen selling gutka pouches.Objective: The objective of this study was to assess the attitude and views of Jammu adult population toward the sale andconsumption on ST by Jammu and Kashmir Government.Materials and Methods: A cross-sectional survey was carried out among the general adult population of Jammu city. 400respondents completed a questionnaire on tobacco use, knowledge of existence of law, health warning, cost increase, andhazards related to ST.Results: Half of the current users (51.6%) surveyed compared to the past users (61.4%) and non-users (69.7%) had knowledgeabout laws on gutka products. Significantly higher percentage of the current users (52.1%) and past users (57.9%) indicatedthat the actions against tobacco products would be slightly effective (P < 0.05). 52.5–68.4% of respondents were aware ofhealth warning signs printed on the tobacco packet. 59.1% of the current users reported easy availability of gutka. The pastusers (54.4%) reported an increase in black marketing of ST gutka.Conclusion: The sale and consumption ban and increased taxes by the government are an effective measure for the improvementof health and reduce consumption. They demonstrate that there is a need for greater public education and the policy has beenlagging behind to curb the black market sale.