RESUMEN
A rare case of urinary tract infection caused by Shigella sonnei is described in a renal transplant recipient adult female on immuno-suppressive therapy. The patient improved and urine cultures became negative after a course of intravenous cefotaxime, given in doses of 1 gm 8 hourly for seven days. The role of S.sonnei in extra-intestinal infections is reviewed
Asunto(s)
Humanos , Femenino , Infecciones Urinarias/diagnóstico , Shigella sonnei/patogenicidad , Infecciones Urinarias/microbiología , Terapia de InmunosupresiónRESUMEN
Comenta-se nesta breve revisao a participacao e o significado de Shigella em processos de infeccao alimentar. Sao tambem abordados as caracteristicas do microrganismo, seus fatores de virulencia e determinancia genetica.Aspectos epidemiologicos da infeccao, bem como, condicoes de crescimento e metodos de deteccao em alimentos, sao tambem abordados
Asunto(s)
Humanos , Disentería Bacilar/diagnóstico , Disentería Bacilar/epidemiología , Disentería Bacilar/patología , Disentería Bacilar/prevención & control , Manipulación de Alimentos/métodos , Shigella boydii/crecimiento & desarrollo , Shigella boydii/patogenicidad , Shigella dysenteriae/crecimiento & desarrollo , Shigella dysenteriae/patogenicidad , Shigella flexneri/crecimiento & desarrollo , Shigella flexneri/patogenicidad , Shigella sonnei/crecimiento & desarrollo , Shigella sonnei/patogenicidad , Virulencia , Contaminación de Alimentos/prevención & control , Higiene Alimentaria , Industria de Procesamiento de Alimentos/métodos , Industria de Procesamiento de Alimentos , Infecciones Bacterianas/transmisión , Intestinos/patologíaRESUMEN
A total of 48 isolates of Shigella species obtained from the Military Central Laboratories was examined for serotype, antibiotic resistance and invasiveness. The transferability and molecular structure of the virulence plasmids from each isolate were also examined. Twenty strains were evasive and 70% of these virulent strains were multidrug resistant. Ten virulent strains [tra+] transferred ampicillin resistance and virulence simultaneously, i.e. they carried conjugative plasmids; while the other strains [10 strains] were tra-. By plasmid analysis and DNA homology, almost all the virulent strains carried a large plasmid of 230 Kb, and 2-3 small cryptic plasmids [6.4, 3.3 and 2.7 Kb]. The results suggested that the cryptic plasmids can be transferred to other strains of the same species by conjugation or mobilization, predicting that the virulent multidrug resistant strains may no longer be restricted to a narrow range of serotypes in the near future. Further genetic analysis of virulence plasmids may be essential for the development of recombinant vaccines against Shigella species
Asunto(s)
Virulencia , Plásmidos/análisis , Shigella boydii/patogenicidad , Shigella dysenteriae/patogenicidad , Shigella flexneri/patogenicidad , Shigella sonnei/patogenicidadRESUMEN
Se presenta un caso de diarrea por triple etiología (Shigella Campylobacter-criptosporidium) en una niña de 3 meses y medio de edad, quién ingresó al Hospital Nacional de Niños en mayo de 1984