Current updates in acute traumatic aortic injury: radiologic diagnosis and management

Acute traumatic aortic injuries, which have substantial lethal outcomes at the time of admission, are fatal in 80% to 90% of cases. These injuries are relatively rare and have nonspecific clinical presentations. Radiologists and emergency physicians need to identify the radiological signs of acute traumatic aortic injury and differentiate them from common imaging errors to ensure accurate diagnosis and determine appropriate management protocols. In combination with image-guided interventions, advances in cross-sectional imaging have enabled nonsurgical management of acute traumatic aortic injuries. Timely and precise diagnoses of these injuries following prompt treatment are essential as up to 90% of patients presenting at the hospital can undergo early repair.

Morphometric Study Of Foramen Magnum Of Skull In Population Of Uttar Pradesh

Background: Foramen Magnum (FM) is a latin word meaning the largest aperture in the base of the skull. It is ovaland wider behind, with the greatest diameter (dm) being antero-posterior (AP). The major vital neuroanatomicpasses through this largest foramen. Many authors have classified FM depending upon its shapes.Objectives: To determine the morphometric parameters of Foramen MagnumMaterials and Methods: The study was conducted on 71 dry human skulls of unknown sex and measured itsAntero-Posterior, Transverse, Right Oblique and Left Oblique diameters with the help of digital caliper.Result: The dormancy of Oval shaped Foramen Magnum was found in this study. The range of Antero-posteriorand Transverse diameter falls between 30.22-40.9 mm and 22.67-33.36 mm respectively. The range of Rightoblique and Left Oblique diameter was found in between 20.84-35.52 mm and 28.88-35.47 mm respectively.Conclusion: The present study will useful not only for anatomists but also in neurosurgery. As the nomenclatureof the opening in the occipital bone at the base of the skull and bounded by Oval and Rounded on visualizationsupported by Antero-Posterior and Transverse diameter of the opening.

Blepharophimosis Ptosis Epicanthus Inversus Syndrome (BPES) type 1 in an Indian Family / Journal of the ASEAN Federation of Endocrine Societies

@#Blepharophimosis ptosis epicanthus inversus (BPES) is a relatively rare congenital disorder, which usually presents with classical eye manifestations. In some cases, it is associated with premature ovarian failure (POF). BPES is of two types, type I and type II. Type I is associated with POF along with eyelid malformations, while Type 2 has only eyelid malformations. Here, we report a family of BPES, in whom two sisters presented with secondary amenorrhea. On eye examination, they have blepharophimosis, ptosis, epicanthus inversus and telecanthus. Investigations revealed hypergonadotropic hypogonadism. Their father also has similar eye manifestations. Diagnosis of BPES type I was made and both were started on hormone replacement therapy. To make timely diagnosis of BPES, every patient with POF should specifically be checked for eye manifestations.

McCune-Albright Syndrome with hypophosphatemic rickets / Journal of the ASEAN Federation of Endocrine Societies

@#Fibrous dysplasia (FD) is sometimes accompanied by extraskeletal manifestations that can include any combination of café-au-lait macules, hyperfunctioning endocrinopathies, such as gonadotropin-independent precocious puberty, hyperthyroidism, growth hormone excess, FGF23-mediated renal phosphate wasting, and/or Cushing’s syndrome, as well as other less common features. The combination of any of these findings, with or without FD, is known as McCune-Albright syndrome (MAS). The broad spectrum of involved tissues and the unpredictable combination of findings is because of a molecular defect due to dominant activating mutations in the widely expressed signalling protein Gsα. These mutations arise sporadically, often early in development, prior to gastrulation and can distribute across many or few tissues.1,2 We present a case of a 3½ year-old-girl who presented simultaneously with precocious puberty and hypophosphatemic rickets, along with fibrous dysplasia and café au lait macules.

Antidiarrhoeal activity on platycladus orieantalis extract.

Platycladus is a distinct genus of evergreen coniferous tree in the cypress family Cupressaceae, containing only one species, Platycladus orientalis, also known as Chinese Arborvitae or Biota. It is a small, slowgrowing tree, to 15-20 m tall and 0.5 m trunk diameterThe different parts of the plant are traditionally used as a diuretic, anticancer, anticonvulsant, stomachic, antipyretic, analgesic and anthelmintic [4,5 ]. The plant has not been explored for its anti diarrhoeal activity so far. The bio active fraction has been prove that it contain three major iridoid glycosides. These iridoids glycoside was subjected to anti diarrhoeal activity against validated experimental models like Castor oil induced diarrhea, gastrointestinal motility tests & PGE2-induced enteropooling. The extract inhibited castor oil induced diarrhoea and PGE2 induced enteropooling in rats; it also reduced gastrointestinal motility after charcoal meal administration. The obtained data demonstrated the excellent anti-diarrhoeal activity of P.Orieantalis and thus have great potential as a source for natural health products.

Antipyretic activity of platycladus orieantalis leaves extract in rat.

The study was conducted to screen the antipyretic activity of alcoholic extract of the leaf of Platycladus Orieantalis .Platycladus Orieantalis is a potent medicinal plant in the Indian systems of medicine. Traditionally it is used as a diuretic, anticancer, anticonvulsant, stomachic, antipyretic, analgesic, etc. In the present study the alcoholic extract of the leaf of Platycladus Orieantalis were studied for their antipyretic activity by Brewer’s yeast-induced pyrexia in rats. It was observed that the alcoholic extract produced significant antipyretic activity (p < 0.05). The extract showed marked antipyretic activity in a dose dependent manner.