Sex Association with HLA-A, -B and -C antigens among bahrainis

This is the first study of HLA class I antigens among Bahrainis, which will indicate the HLA -A, -B, and -C amongst Bahrainis in correlation with sex of the population. Six hundred and five Bahrainis were included in the study [303 males: 302 females]. The complement-dependent microcytotoxicity [CDC] was used. The study showed that there are unique HLA antigens, which show Bahrainis relation to the Middle East, with the following characteristics of high frequencies: A2, Al, A19, A9, Al0, All, B12, B7, B8, B2, B5, B13, Cw4, Cw3, Cw1, Cw2, and Cw6. Some of the antigens were shared with other countries. The results showed that some HLA -A, -B and -C antigens are sex associated