Tubular enteric duplication presenting as jejuno-colic fistula in a 38 years old adult

Colo-enteric fistula is a rare entity, malignancy being the commonest cause. Both adenocarcinoma and rarely lymphoma have been known to cause it. Benign jejuno-colic fistulas are mostly secondary to tuberculosis or inflammatory bowel disease. Here we present a case of a young adult male, who presented with altered bowel habits. Colonoscopy and oesophago-gastro-duodenoscopy (OGD) revealed a fistulous tract between the proximal jejunum to the splenic flexure of colon. Surgery revealed a small fistulous connection between the above-mentioned parts of the bowel about 1cm long. Histopathology demonstrated it to have all the layers of the intestinal anatomy, hence indicating a possibility of congenital aetiology, probably enteric duplication of communicating tubular variety.

[Determination of naphthodianthrones, phloroglucinol and flavonoids from three species of hypericum genus in some areas of Syria by high performance liquid chromatography [HPLC] - UV detector]

In this study, eight main active constituents in the aerial parts [leaves, stems, flowering tops, fruiting tops and roots] were determined quantitavelly of three species of hypericum genus, which are H. perforatum, H. langinosum, H. triquetrifolium. We determined five flavonoids[hyperoside, isoquercitrin, quercitrin, quercetin, rutin], two naphthodianthrones [hypericin, pseudohypericin] and phloroglucinol [hyperforin] by HPLC - UV detector. The study show that these species differ chemically from each others according to the concentration and presence or absent of active studied components in the different vegetal parts of studied species. The detailed morphological study of H. perforatum show that there are two varieties narrowleaved and broadleaved, which also differ from each other chemically, but the two varieties without rutin in all plant parts

Possible association of HLA-DR and DQ molecules with colorectal cancer in Iraqi patients

Human leukocyte antigen [HLA] is the most polymorphic genetic system in man. The genes of this region influnence susceptibility to certain diseases. This study was established to shed light on the possible association of HLA class-II antigens and CRC patients, and to correlate the findings with both family history and tumor location. Microlymphocytotxicity assay has been used to assess HLA-typing of 150 blood samples of 100 CRC patients and 50 healthy normal control. An increased frequency of HLA-DR7 was observed for patients' group versus control group with P-value [<0.005], moreover, statistical analysis showed non significant correlation of HLA-DR7 with both family history of CRC and tumor location. This finding demonstrate that HLA-DR7 might play a role in CRC susceptibility