Effect of dexamethasone on the expression of ICH and APQ-4 in brain tissue of hematoma in rats / 中国生化药物杂志

Objective To investigate the effect of dexamethasone on the expression of APQ-4 and cytokines in the hematoma and brain tissue of ICH rats. Methods The treatment group was treated with injection of 1mg/kg and dexamethasone, and the model group and the sham operation group were injected with the same amount of normal saline. Results The model group APQ-4, TNF- positive cells. The proportion of second, third, the highest in the 7d after the operation, the sham operation group was the lowest (P<0.05). Conclusion Dexamethasone is beneficial to reduce the APQ-4 expression in brain tissue of rats in ICH, while reducing the expression of TNF- alpha.

Statistical Analysis and Countermeasure of Drug Return in the Dispensary for Inpatients in Our Hospital During 2004～2006 / 中国药房

OBJECTIVE: To analyze the drug return in our hospital and to put forward countermeasures.METHODS: The drug return in our hospital from 2004 to 2006 was analyzed retrospectively in respect of the amount of money,drug variety and causes.RESULTS: The amount of money of returned drugs increased rapidly in 2005 than the previous year,but decreased in 2006.The major varieties were injectable drugs,followed by anti-infective drugs.Doctors' modification of medical orders was the main reason accountable for drug return.CONCLUSION: It is suggested that effective measures be taken in hospital to strengthen publicizing and management on the rational drug use,standardize procedure of drug return,and improve hospital computer system etc.

Reasonable Arrangement to Improve the Working Quality in PIVAS / 中国药房

OBJECTIVE:To summarize the key issues such as the drug waste and the phone calls affecting the working efficiency in pharmacy intravenous admixture service(PIVAS)and to put forward countermeasures so as to improve the working quality there.METHODS:The records about the drug waste in PIVAS and the phone calls that affected the working efficiency from clinical departments were analyzed statistically.RESULTS:Dispensing error and drug return were the main factors accountable for the drug waste in PIVAS.The proportion of phone calls from clinical departments demanding drug bills and drug dispensing was the highest,which greatly affected the working efficiency in PIVAS.CONCLUSIONS:The clinical staff should be informed not to make the unnecessary calls to PIVAS so as to improve the working quality in PIVAS.