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Braz. j. infect. dis ; 6(3): 129-135, Jun. 2002.
Article Dans Anglais | LILACS, SES-SP | ID: lil-332322

Résumé

HIV-infected women from S o Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD(4)(+) cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5). Twenty (7.5) women were infected by one or more low-risk viruses, 89 (33) by one or more high-risk viruses, and 64 (24) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19 of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD(4)/microL <100) were at the greatest risk of having a cytological abnormality and a high high-risk HPV viral load.


Sujets)
Humains , Femelle , Adolescent , Adulte , Adulte d'âge moyen , Tumeurs du col de l'utérus , Charge virale , Infections à VIH/complications , Infections à VIH/virologie , Infections à papillomavirus/complications , Infections à papillomavirus/virologie , Infections à virus oncogènes/complications , Papillomaviridae , Brésil , ADN viral , Tumeurs du col de l'utérus , Prévalence , Facteurs de risque , VIH (Virus de l'Immunodéficience Humaine) , Frottis vaginaux , Facteurs âges , Infections à papillomavirus/épidémiologie , Infections à virus oncogènes/épidémiologie , Infections à virus oncogènes/virologie , Tumeurs épidermoïdes/complications , Tumeurs épidermoïdes/épidémiologie , Tumeurs épidermoïdes/virologie
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