Follow up of diabetic complications

Some research found that certain diabetic complications occur more frequently in some racial minority groups. Rate of diabetic complications in real-world practice is higher than expected from the clinical trial setting, especially among patients with complications at diagnosis. This suggests that in diabetic patients racial differences may exist in macro vascular and micro vascular disease frequency. 340 diabetic patients were chosen randomly from out patients' clinic of the national institute of diabetes and endocrinology. They received conventional treatment.by different doctors with no special protocol for treatment and was examined twice once at 2004 and another at 2006. Our result showed that during three year there are significant deterioration in weight, BMI. ECG, retinopathy, FBS, AST, ALT, cholesterol, triglyceride, urea, uric acid, GFR, HBlAC.And there were significant improve as regard BP, ACR, LDL. The major complications develop by Egyptian diabetic patients within 3 years follow up was increase percent of retinopathy [27%], followed by teeth loss [23%] then IHD [5%] with no patient develop ESRD. also there are deterioration of GFR.. As regard risk factors there is deterioration in cholesterol followed by waist circumference, BMI, triglyceride then HDL.but significant improve in BP control In Egyptian diabetic patient nudus examination and lipid profile must checked regularly every three moth

Effect of hypertension on retinopathy and nephropathy in diabetic patients

This study investigated the impact of hypertension on the prevalence of diabetic nephropathy and retinopathy. Two hundred hypertensive diabetic patients and two hundred non hypertensive diabetic patients were investigated for fundus changes and renal changes. The mean values and standard deviation for diabetic hypertension groups were:-urea [27.8+/-11 mg/dl], creatinine [0.9+/-0.27 mg/dl], Microalbuminuria <30mg [16 +/-6.9 mg/l] Microalbumiuria >30mg [100+/-79], creatinineclearance [81.5+/-28.6 ml/min], Glycated HB [9.82+/-3.01%], FBS[190+88.3 mg/dl], cholesterol [214+/-78 mg/dl] triglyceride [167+/-99.2 mg/dl]. color blindness 15 cases out of 110 cases and retinopathy 23 cases out of 123 cases. For the non hypertension group the values and standard deviation were: Urea [25.5 +/-11.3 mg/dl], Creatinine [0.82+/-0.22 mg/dl], Microalbuminu <30mg [16.7 +/-6.1 mg/l/day], microalbuminuria >30mg [104 +/-82 mg/l], Creatinineclearance [91.9 +/-27.8 mum], Glycated HB [9.42 +/-2.69%], FBS [192+/-83.9mg/dl]. cholesterol [218+/-68.3 mg/dl], Triglyceride [186+/-139 mg/dl] Color blindness l5cases out of 137cases.and retinopathy 13 case out of 127 case . There was a statistical significant difference for urea [p<0.05], creatinine [p<0.002], Creatinine clearance [p<0.001] and retinopathy [p<0.04] for the hypertensive group in comparison to non hypertensive group. There was also non significant decrease in renal function as micro albuminuria increase above 30 mg in both groups

Conclusion: hypertension had a deleterious effect on the prevalence of retinopathy and nephropathy in diabetic patients