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1.
Korean Journal of Medicine ; : S106-S110, 2011.
Article Dans Coréen | WPRIM | ID: wpr-36742

Résumé

Autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and primary biliary cirrhosis (PBC) are the major immune-mediated chronic liver diseases. They are characterized by circulating autoantibodies, hypergammaglobulinemia, unique clinical features, and associations with other autoimmune diseases, such as inflammatory bowel disease and autoimmune thyroiditis. Primary biliary cirrhosis is known to be associated with inflammatory bowel disease, such as ulcerative colitis. On the other hand, autoimmune hepatitis is rarely associated with ulcerative colitis. Here, we report a case diagnosed as autoimmune hepatitis combined with ulcerative colitis on the basis of histological and endoscopic findings.


Sujets)
Autoanticorps , Maladies auto-immunes , Angiocholite sclérosante , Rectocolite hémorragique , Main , Hépatite auto-immune , Hypergammaglobulinémie , Maladies inflammatoires intestinales , Cirrhose biliaire , Maladies du foie , Thyroïdite auto-immune , Ulcère
2.
Korean Journal of Gastrointestinal Endoscopy ; : 21-24, 2011.
Article Dans Coréen | WPRIM | ID: wpr-193607

Résumé

Cytomegalovirus (CMV) is a potentially important pathogen in an immunocompromised host. CMV infection usually occurs in patients with severe immune deficiency, such as acquired immunodeficiency syndrome, organ transplantation, malignant disease, or immunosuppressive therapy. CMV can cause ulcerations anywhere in the GI tract ranging from the esophagus to the rectum, but the colon is the most susceptible organ in the GI tract. CMV infection rarely occurs but generally causes an asymptomatic or mildly symptomatic acute illness in immunocompetent patients. Some patients with gastrointestinal CMV disease do not require antiviral treatment such as ganciclovir and frequently recover with supportive therapy. Although in immunocompetent patients, antiviral therapy may be needed based on age, chronic illness, or treatment response. We experienced a case of CMV-induced multiple gastric ulcers with severe epigastric pain in an immunocompetent patient who fully recovered with supportive therapy including a proton pump inhibitor.


Sujets)
Humains , Syndrome d'immunodéficience acquise , Maladie chronique , Côlon , Cytomegalovirus , Oesophage , Ganciclovir , Tube digestif , Sujet immunodéprimé , Transplantation d'organe , Pompes à protons , Rectum , Ulcère gastrique , Transplants , Ulcère
3.
Korean Circulation Journal ; : 339-342, 2010.
Article Dans Anglais | WPRIM | ID: wpr-196627

Résumé

LEOPARD syndrome (LS) is a rare hereditary disorder in Asian countries. This syndrome consists of multiple systemic abnormalities. In particular, characteristic cardiovascular effects in LS may include variable clinical manifestations from benign to life-threatening courses. The cardiac effects of this syndrome consist of left ventricular hypertrophy (LVH), pulmonary stenosis (PS), coronary artery dilatation and electrocardiogram(ECG) abnormalities. Since there are few LS patients who have undergone a complete cardiovascular evaluation, the nature and clinical prognosis of cardiovascular abnormalities in this syndrome remain uncertain. Also, there have been few reports on therapeutic strategies for cardiovascular abnormalities in LS. Here we describe a case of LS who presented with multiple cardiovascular problems and underwent successful surgical and medical treatment.


Sujets)
Humains , Asiatiques , Malformations cardiovasculaires , Vaisseaux coronaires , Dilatation , Hypertrophie ventriculaire gauche , Lentigo , Syndrome LEOPARD , Panthera , Pronostic , Sténose de la valve pulmonaire
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