Your browser doesn't support javascript.
loading
Montrer: 20 | 50 | 100
Résultats 1 - 1 de 1
Filtre
Ajouter des filtres








Gamme d'année
1.
Indian J Biochem Biophys ; 2014 Dec ; 51(6): 506-511
Article Dans Anglais | IMSEAR | ID: sea-156530

Résumé

N-myristoyltransferase (NMT) is an essential eukaryotic enzyme which catalyzes the transfer of the myristoyl group to the terminal glycine residue of a number of proteins including those involved in signal transduction and apoptotic pathways. In higher eukaryotes, two isoforms of NMT have been identified (NMT1 and NMT2) which share about 76% amino acid sequence identity in humans. Protein-protein interactions of NMTs reveal that m-calpain interacts with NMT1 whereas caspase-3 interacts with NMT2. These findings reveal differential interactions of both isoforms of NMT with various signaling molecules. This minireview provides an overview of the regulation of N-myristoyltransferase by calpain and caspase systems.


Sujets)
Acyltransferases/métabolisme , Animaux , Calpain/métabolisme , Caspases/métabolisme , Régulation de l'expression des gènes codant pour des enzymes/physiologie , Humains , Métabolisme lipidique/physiologie , Modèles biologiques , Transduction du signal/physiologie
SÉLECTION CITATIONS
Détails de la recherche