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1.
Indian J Pathol Microbiol ; 2003 Apr; 46(2): 226-8
Article Dans Anglais | IMSEAR | ID: sea-73858

Résumé

Mesenchymal hamartoma of the liver is a rare benign tumor of infancy and childhood. A case of mesenchymal hamartoma of liver seen in a 37 day old child is reported and the available literature on the subject is briefly reviewed.


Sujets)
Hamartomes/anatomopathologie , Humains , Nourrisson , Tumeurs du foie/anatomopathologie , Mâle
2.
Indian J Cancer ; 1995 Mar; 32(1): 27-30
Article Dans Anglais | IMSEAR | ID: sea-49363

Résumé

A case of segmental renal dysplasia presenting with loin pain, a renal mass and hypertension in a young girl of 16 years is being reported. Clinical and histological features of this rare renal anomaly are discussed.


Sujets)
Adolescent , Femelle , Humains , Rein/malformations
3.
Article Dans Anglais | IMSEAR | ID: sea-124997

Résumé

Generalised peritonitis is a common and dreaded surgical emergency. Its tropical spectrum continues to be different from its western counterpart. The study represents a retrospective analysis of 250 cases of peritonitis managed surgically over a decade at a large referral surgical unit at New Delhi. Perforations of the upper gastrointestinal tract viz: duodenal ulcer, enteric perforations etc. constitute the majority unlike western series where lower gastrointestinal tract perforations predominate. Despite significant delays in presentation, the overall prognosis remains comparable to the western figures. A comparatively younger age group involved may be responsible for better outcome.


Sujets)
Adulte , Appendicite/complications , Femelle , Humains , Inde/épidémiologie , Perforation intestinale/complications , Mâle , Perforation d'ulcère gastroduodénal/complications , Péritonite/épidémiologie , Rupture spontanée , Tuberculose gastro-intestinale/complications , Fièvre typhoïde/complications
4.
Indian J Cancer ; 1994 Jun; 31(2): 72-7
Article Dans Anglais | IMSEAR | ID: sea-50252

Résumé

Twenty eight patients of sporadic primary hyperparathyroidism seen over a period of 10 years were studied. There were 18 females and 10 males with a mean age of 35.9 years. Bone involvement was the commonest clinical presentation (90%) followed by renal involvement (65%) and more than half the patients (54%) had involvement of both the skeletal and renal systems. The tumor was clinically palapable in six patients. Thalliumtechnetium subtraction scan had a sensitivity of 87% followed by computerised tomography (70%), and ultrasound (65%) in diagnosing parathyroid pathology. All the patients underwent surgical excision of the abnormal gland (S). Adenomas constituted the single largest group (90%). Histologically, only 32% of the patients had chief cell morphology. Clear cell (32%) mixed cell, and oxyphil cell (7.2%) types accounted for the remaining adenomas. Majority of the patients (82%) had symptomatic postoperative hypocalcemia requiring intravenous calcium with or without vitamin D supplementation. In contrast to western reports most of our patients were young, presented late with florid bone and renal disease and had large palpable tumors.


Sujets)
Adénomes/complications , Adolescent , Adulte , Sujet âgé , Phosphatase alcaline/sang , Calcium/sang , Enfant , Femelle , Humains , Hyperparathyroïdie/sang , Mâle , Adulte d'âge moyen , Tumeurs de la parathyroïde/complications , Études rétrospectives
6.
7.
Indian J Cancer ; 1991 Dec; 28(4): 196-201
Article Dans Anglais | IMSEAR | ID: sea-50258

Résumé

Ketoconazole, an imidazole derivative is known to decrease adrenal steroid biosynthesis by inhibiting cytochrome P450 dependent adrenal enzymes. Three patients of adrenal carcinoma treated with ketoconazole, 600-1200 mg daily showed significant fall in plasma and urinary cortisol levels, but no reduction in tumor size, one patient developed liver dysfunction which reverted back to normal on discontinuing the drug.


Sujets)
Adolescent , Tumeurs corticosurrénaliennes/traitement médicamenteux , Adulte , Enfant , Femelle , Humains , Kétoconazole/usage thérapeutique , Mâle
8.
Article Dans Anglais | IMSEAR | ID: sea-125045

Résumé

Introduction of 'silent' exocrine atrophy (and endocrine 'enrichment') in pancreatic grafts following ductular blockade may have a role in human diabetes by circumventing currently elusive islet isolation/purification protocols. To explore this potential, pancreatic isografts were performed in 12 pairs of inbred Wistar NIN rats. Donor pancreatectomy was performed after distal clamping and canulation of common bile duct and injection of 0.5 ml. polyacrylamide gel (blocked n = 7) or normal saline (un-blocked n = 5) respectively. One to 2 m.m. fragments of the resulting mildly distended pancreases were transplanted in to 2 sites (renal capsule and iliac fossa subcutaneously) of cach recipient. Post-operative biopsies of the transplanted grafts (unilateral nephrectomy and iliac fossa biopsies) revealed macroscopic and microscopic evidence of necrotizing pancreatitis in both the groups at both the sites (histiocytic and giant cell infiltration, fat necrosis and focal calcification with destruction of exocrine and endocrine cells) as early as 1 and 3 weeks. Possible detrimental factors include: volume and pressure of ductal injection, graft sites (confined spaces), post-operative wound infection and bio-compatibility of the material used for ductular blockade.


Sujets)
Résines acryliques , Animaux , Conduit cholédoque , Gels , Transplantation d'ilots de Langerhans/méthodes , Conduits pancréatiques , Prothèses et implants , Rats , Lignées consanguines de rats
14.
Indian Pediatr ; 1986 Feb; 23(2): 97-100
Article Dans Anglais | IMSEAR | ID: sea-14286
20.
Indian Pediatr ; 1982 Oct; 19(10): 878-9
Article Dans Anglais | IMSEAR | ID: sea-14594
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