Immunohistochemical detection of the c-erb B-2 oncogene and the p53 tumor supressor gene in malignant and non malignant breast lesions and their prognostic significance

In a series of 50 breast lesions [31 malignant breast lesions and 19 benign breast lesions], expression of p53 protein and overexpression of c-erb B-2 oncoprotein were examined immunohistochemically. Expression of p53 was present in 17 out of 31 malignant cases. Five cases were infiltrated duct carcinoma grade II [IDC GII], nine cases were infiltrated duct carcinoma grade III [IDC GIII], two cases were mucoid carcinoma and one case was squamous cell carcinoma. No expression of p53 in invasive lobular carcinoma [ILC] was detected

Esophagectomy by inversion stripping and stapled esophago-gastroanastomosis: a cadaveric and animal study

Numerous esophagectomy techniques are available, of them transhiatal esophagectomy gives lower morbidity and mortality than esophagectomy involving a thoracotomy. The new technique of esophageal stripping with stapled esophagogastric anastomosis was peirformed on 8 human cadavers and on 9 live dogs. Stripping in a neck to abdomen direction was easy, quick and safe. Modifying the stripper head to accept the two wire ends made pulling up the stomach to the neck easy and safe. Using staplers to perform the procedure decreased the operative time. The authors think that this new technique is suitable for esophagectomy for upper 1/3 and lower 1/3 esophageal tumours as well as for esophagectomy for all benign conditions requiring removal of the esophagus