Progress on ferroptosis in pregnancy-related diseases / 中华围产医学杂志

Ferroptosis, a new form of programmed cell death, could be regulated by lipid metabolism, amino acid metabolism, and iron metabolism. Ferroptosis is closely related to human physiological mechanisms and involved in the development and progression of multiple diseases. More and more researchers have found that ferroptosis also plays a vital role in pregnancy-related disorders such as preeclampsia, gestational diabetes, and miscarriage. However, the mechanisms have not yet been fully understood. This article reviews the progress in ferroptosis in pregnancy-related diseases to provide new directions for scientific research and clinical treatment.

Correlation analysis between family function and disease benefit in patients with chronic obstructive pulmonary disease / 中国实用护理杂志

Objective:To investigate and analyze the correlation between family function and disease benefit perception among patients with chronic obstructive pulmonary disease (COPD).Methods:A cross-sectional study, convenient sampling method, family function Assessment Scale (APGAR) and disease benefit scale were used to investigate the family function assessment and disease benefit of 172 COPD patients in the respiratory department of Yinchuan First People ′s Hospital from January to April 2021. Results:The total score of family function in COPD patients was (7.74 ± 2.50) points, and the total score of disease benefit was (53.24 ± 7.03) points. There was a positive correlation between family function and disease benefit in COPD patients ( r values were 0.041-0.275, P<0.05). Conclusions:The disease benefit of COPD patients was closely related to family function, and improving the level of family function support can improve the disease benefit of COPD patients.

Advances in exosomal microRNA and pathogenesis of preeclampsia / 中华围产医学杂志

Preeclampsia is an idiopathic gestational disease with unknown etiology or pathogenesis. Exosomes are membranous nanovesicles secreted by various cells, carrying contents such as proteins, mRNA, microRNA and lipids and being involved in regulations between cells by transporting the above contents through target cells. The expression of exosome-derived proteins and microRNAs in preeclampsia patients experiences changes, resulting in maternal inadequate trophoblast invasion, depressed endothelial cell function and angiogenesis. Research on placenta-derived exosomal microRNAs in preeclampsia patients may help to elucidate the pathogenesis of preeclampsia.