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1.
Clinics ; 75: e1698, 2020. tab
Article Dans Anglais | LILACS | ID: biblio-1101087

Résumé

OBJECTIVE: To report initial experience from the use of extracorporeal membrane oxygenation (ECMO) in patients who received lung transplantation. METHODS: Retrospective study of a single tertiary center in the Brazilian state of São Paulo, a national reference in lung transplantation, based on the prospective collection of data from electronic medical records. The period analyzed extended from January 2009 (beginning of the program) until December 2018. RESULTS: A total of 75 lung transplants were performed, with ECMO used in 8 (10.7%) cases. Of the patients, 4 (50%) were female. The mean age was 46.4±14.3 years. The causes of the end-stage lung disease that led to transplantation were pulmonary arterial hypertension in 3 (37.5%) patients, bronchiectasis in 2 (25%) patients, pulmonary fibrosis in 2 (25%) patients, and pulmonary emphysema in 1 (12.5%) patient. In our series, 7 (87.5%) cases were sequential bilateral transplantations. Prioritization was necessary in 4 (50%) patients, and in 1 patient, ECMO was used as a bridge to transplantation. The ECMO route was central in 4 (50%), peripheral venovenous in 2 (25%) and peripheral venoarterial in 2 (25%) patients. The mean length of the intensive care unit (ICU) stay was 14±7.5 days and of the hospital stay was 34.1±34.2 days. The mean ECMO duration was 9.3±6.6 days with a 50% decannulation rate. Three patients were discharged (37.5%). CONCLUSION: Lung transplantation requires complex treatment, and ECMO has allowed extending the indications for transplantation and provided adjuvant support in the clinical management of these patients.


Sujets)
Oxygénation extracorporelle sur oxygénateur à membrane/méthodes , Maladies pulmonaires/thérapie , Complications postopératoires , Emphysème pulmonaire/thérapie , Emphysème pulmonaire/épidémiologie , Fibrose pulmonaire/thérapie , Fibrose pulmonaire/épidémiologie , Facteurs temps , Brésil/épidémiologie , Dilatation des bronches/thérapie , Dilatation des bronches/épidémiologie , Études prospectives , Études rétrospectives , Transplantation pulmonaire/méthodes , Résultat thérapeutique , Hypertension artérielle pulmonaire primitive familiale/thérapie , Hypertension artérielle pulmonaire primitive familiale/épidémiologie , Unités de soins intensifs , Durée du séjour , Maladies pulmonaires/épidémiologie
7.
Indian J Chest Dis Allied Sci ; 1980 Oct-Dec; 22(4): 214-9
Article Dans Anglais | IMSEAR | ID: sea-29184
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