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1.
Journal of Neyshabur University of Medical Sciences. 2016; 4 (2): 41-48
em Persa | IMEMR | ID: emr-185573

RESUMO

Introduction and Aims: In the event of damage to the skin, the epidermis of which goes to the disintegration of the body, is a wound that is common in diabetics. The purpose of this study was to evaluate the effect of aqueous extract of grape [Vitis Vinifera] on wound healing in diabetic Wistar rat


Materials and Methods: In this study 48 male Wistar rats were divided into 4 groups [control, sham, experimental 1, empirical 2] were tested. The extra pawn injured area of 3 cm to the left of the spine created. Extract-treated group compared to one in three [aqueous extract + eucerin] received. Wound healing was examined microscopically during 21 days


Results: Wound healing in group that became diabetes using streptozocin [the diabetic rats], showed late recovery compared to normal wound healing in normal groups and wound healing in experimental groups treated with aqueous extract of grape was accelerated compared control group


Conclusion: The results showed that the aqueous extract of grape skin accelerate wound healing in normal and diabetic samples

2.
Journal of Paramedical Sciences. 2015; 6 (2): 79-84
em Inglês | IMEMR | ID: emr-186269

RESUMO

Information about the health risks that might be associated with lipstick consumption effects is scarce in the literature. The present work investigated the bioaccumulation of lead [Pb] in brain of rats originated from lipstick sample. First, Lead contents were determined in 12 different brands of lipsticks. Lead was detected in all the studied samples. The average lead content in 14 lipsticks samples was 12.2 PPM wet wt. Then, one brand was selected for feeding to the rats and amount of oral exposing in the three doses was calculated. Sixty rats were used for the experiment. Animals were divided into 4 groups of 15 animals each. While 1group served as control group, the remaining 3 groups were exposed to lipstick through oral gavage for 12 weeks. Results show that, exposure to the lipstick cause significantly disposition of lead in the brain of rats

3.
IJFS-International Journal of Fertility and Sterility. 2012; 5 (4): 197-202
em Inglês | IMEMR | ID: emr-163645

RESUMO

Background: Arresting at a certain stage of development like the two-cell stage could be one of the causes of infertility. The aim of this study is to evaluate the effects of ethanol and strontium on growth and development of mice embryos arrested at the two-cell stage


Materials and Methods: In this experimental study, female mice were coupled with a male following superovulation. Positive vaginal plug mice were sacrificed 48 hours after human chorionic gonadotropin [hCG] injection. Two-cell embryos were transferred to M16 medium and divided to four groups. The first control group was incubated without any exposure to low temperatures. Groups 2, 3 and 4 were exposed to 4[degree]C for 24 hours. The second control group was incubated immediately, while the third and fourth groups were exposed to 10 mM strontium for five minutes and 0.1% ethanol for a further five minutes. Growth rate and developmental parameters of embryos were analyzed by one-way ANOVA. The significant difference between the groups was determined by Post Hoc


Results: The data shows that developmental rate is decreased significantly by 4[degree]C exposure. The mean percentage of degenerated embryo was significantly different between groups but the mean cleavage rate was not significantly different. The mean percent of morula, blastocyst and hatched blastocyst formation were significantly different between groups during a 120 hours study post hCG injection


Conclusion: The effect of strontium and ethanol on arrested two-cell embryos had no significant effect on the mean percentage of morula, but ethanol treatment significantly increased the percentage of blastocyst and hatched blastocyst formation compared to strontium


Assuntos
Animais de Laboratório , Etanol , Camundongos/crescimento & desenvolvimento , Desenvolvimento Embrionário
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