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Introduction: Serum high density lipoproteins levels wereestimated in type II diabetes mellitus patients with differentsystemic complications.Methods: Total 60 subjects (both male & female) of age group35-60 years were selected for the study, of which 30 subjectswere control (nondiabetic). Fasting high density lipoproteinslevels were determined by cholesterol esterase-cholesteroloxidaseperoxidase method. Proportion of differentcomplications was also determined.Conclusion: It was found that average serum values of highdensity lipoproteins in type II diabetes mellitus patients wassignificantly decreased as compared to control group. Majorityof systemic complications were cardiovascular in whichhypertension was commonest. The study indicated a positivecorrelation between serum high density lipoproteins levels andcardiovascular risk in type II diabetic patients
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Background: Vitamin D deficiency is prevalent in the majority parts of the world. The prevalence of vitamin D deficiency in India in urban area 9-11% and in rural area 3-6%. Coronary artery disease is worldwide health problem and consists of variety of heart illness. Vitamin D deficiency may cause cardiovascular events by a variety of potential biological mechanism. Aims & Objectives: To evaluate the role of vitamin D as a rising risk factor for coronary artery disease. Materials & Methods: The study was carried out in department of Cardiology, S.P. Medical College included 50 patients of coronary artery disease admitted in H.R.M. Center Bikaner. The control population comprise of age and sex matched 50 healthy persons. Vitamin D was done on ELISA reader and lipid profile assessment was done on fully automated analyzer. The statistical analysis was done by using SPSS software. The results were articulated as Mean ± SD. The Student t-test was carried out for relationship of the data & P value <0.05 was considered statistically significant. Results: The study discovered that vitamin D level was established to be significantly lower in cases as compared to controls. We also noticed significant difference in mean to total cholesterol, HDL cholesterol and LDL cholesterol in between cases and control. Conclusion: This study concluded that continue follow up of vitamin D will be helpful for measurement of increased risk of coronary artery disease episode beyond the traditional risk factors.
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Objective: To assess the effect of zinc supplementation on neuro-development and growth of preterm neonates. Setting: Referral neonatal unit of a teaching hospital. Design: Open-labeled Randomized controlled trial. Participants: 100 preterm neonates. Intervention: Participants randomized to receive oral zinc (study group) or not (controls). Main Outcome Measures: Primary: Neuro-development status at 40 weeks post conceptional age and at 3 month corrected age using Amiel-Tison neurologic assessment. Secondary: anthropometry and serum alkaline phosphatase at 3 months corrected age. Results: At 40 weeks post-conceptional age, greater number of zinc supplemented infants demonstrated alertness and attention pattern normal for their age (P=0.02). Higher number of controls showed signs of hyper-excitability at 40 week post-conceptional age (P=0.001) and 3 months corrected age (P=0.003). At 3 month corrected age, mean serum alkaline phosphatase level was significantly higher in the study group compared to controls. Conclusion: Zinc supplementation till 3 month corrected age in preterm breastfed infants improves alertness and attention pattern; and decreases signs of hyperexcitability, and proportion with abnormal reflexes.