RESUMO
In this work, three groups of subjects were studied. The first was control group [8 cases], the second was asymptomatic cigarette smokers [30 cases] and the third was symptomatic cigarette smokers [36 cases] that was in turn divided into three equal subgroups: asthma, COPD and cancer lung. All groups were examined for ventilatory function tests [FVC, FEV1 -FEV1% and FEF 25-75%], arterial blood gases, [Pa O2 and PaCO2, pH] and blood levels of lead 212, lead214, and Cesium 137. There was a significant decrease in all ventilalory function tests, PaO 2and increase PaCO2 in symptomatic group in relation to control and asymptomatic groups. The pH of blood showed no change. The study showed a significant increase in the levels of lead 212, lead214 and cesium137 in both smokers groups in relation to control. FEV1 and FEF 25-75%, lead212, lead 214 and cesium 137 showed significant differences between the three studied groups. Also there was a significant negative correlation between the blood lead 212 and the FEV1% in the symptomatic cigarette smokers group. These changes were related to the toxic contents of cigarette leaves and wrappings including the high content of the previously estimated radioisotopes
Assuntos
Humanos , Masculino , Testes de Função Respiratória , Gasometria , Radioisótopos de Chumbo , Radioisótopos de CésioRESUMO
Five groups of rats were used in this study. The first group was used as control, the second was given aspirin for two weeks, the third was given aspirin and natural honey for two weeks, the fourth was treated as the third and left two weeks without treatment, while the fifth was given aspirin as well as sugars in a similar percentage to those present in natural honey for two weeks. The stomach was examined by scanning electron microscopy. The gastric secretion volume, free and total acidity, pepsin, mucoprotein and mucoproteose [concentration and output] were estimated