RESUMO
A prospective study was conducted on 45 cirrhotic subjects admitted in a medical ward following bleeding from oesophageal varices demonstrated on gastroscopy. They were randomized to receive either sclerotherapy alone or sclerotherapy combined with subcutaneous injections of Octreotide. Rebleeding episodes were less common in patients who received sub-sclerotherapy in reducing rebleeding episodes
Assuntos
Humanos , Endoscopia Gastrointestinal , Escleroterapia , Varizes Esofágicas e Gástricas/terapia , Hemorragia Gastrointestinal/tratamento farmacológico , Cirrose Hepática/fisiopatologia , Injeções SubcutâneasRESUMO
A prospective, randomized study was undertaken to determine the long term effect of NSAIDs on lactose absorption. Twenty controls and 28 patients were selected from the general medical out-patients clinic of a teaching hospital, adhering to strict inclusion and exclusion criteria. Six [30%] out of the 20 controls and 21 [75%] out of 28 patients showed positive hydrogen breath test at 60, 90, or 120 minutes [H
ion >20 ppm]; p value at 60 and 120 minutes was statistically significant [p<0.01], whereas at 90 minutes it was highly significant [p<0.001]. It was concluded that patients on long term NSAIDs are more likely to develop lactose malabsorption as indicated by positive breath test. This may have predictive value in picking up early small intestinal inflammation and thus enteropathy which is now a recognized complication of this group of drugs
Assuntos
Intestino Delgado/efeitos dos fármacos , Intolerância à Lactose/induzido quimicamente , Hidrogênio , Estudos Prospectivos/métodosRESUMO
This is a retrospective study of 102 endoscopies performed over a period of one year in patients admitted with proven or suspected upper gastrointestinal haemorrhage. During this period a total of 396 endoscopies were performed. Duodenal ulcer were the commonest lesion found in 34% followed by Gastric ulcer in 23%, and oesophageal varices in 21% of patients. Among predisposing factors, apart from smoking, drugs are becoming increasingly common as a factor in gastric and oesophageal ulcers. We conclude that Duodenal Ulcer is still a common cause of upper gastrointestinal haemorrhage