Anti-inflammatory activity of aerial parts of tephrosia purpurea linn.

The crude extracts of aerial parts of Tephrosia purpurea Linn. was tested for anti-inflammatory activities. The effect of ethanolic and aqueous extracts were investigated in rats to evaluate the anti-inflammatory activity. Carrageenan-induced and histamine-induced rat paw oedema methods were employed to test anti-inflammatory activity. The ethanolic and aqueous extracts [250 mg/kg] showed the inhibition of carrageenan-induced rats paw oedema and also found to be effective in histamine-induced method. The results indicate that both ethanolic and aqueous extracts showed significant [P<0.001] anti-inflammatory activity when compared to control

Local anti-inflammatory and anti-nociceptive activities of coldenia procumbens linn.

The ethanolic extract of the leaves of Coldenia procumbens Linn, was studied in Swiss albino mice against 12-O-tetradecanoylphorbol-13-acetate [TPA] and arachidonic acid [AA] induced inflammatory response, while the analgesic effect was studied using the acetic acid-induced writhing in mice and formalin-induced nociception. The ethanolic extract produced dose dependent anti-inflammatory activity against the pathogens. It also showed an inhibitory effect on pain caused by acetic acid in mice and reduced pain episodes induced by formalin. The results indicated that the ethanolic extract produced significant [P<0.05] anti-inflammatory and anti-nociceptive activity when compared with the standard and untreated control

Antihyperglycemic and hypoglycemic effect of bougainvillea spectabilis linn, in normal and glucose induced diabetic rats

The hypoglycemic effect of ethanolic extract of Bougainvillea spectabilis was investigated on glucose loaded and streptozotocin induced diabetic rats. The blood glucose levels were measured at 0, 1,2 and 3 hrs after the treatment. The ethanolic extract of B. spectabilis [300 mg/kg] reduced the blood glucose of normal rat from 85.33 +/- 1.79 to 65.17 +/- 3.67 mg/dl, 3 hrs after oral administration of the extract [P<0.001]. It also significantly lowered blood glucose level in streptozotocin induced diabetic rat from 330.67 +/- 3.27 to 132.17 +/- 4.49 mg/dl, 3 hrs after oral administration of the extract [p<0.001]. The antihyperglycemic activity of B. spectabilis was compared with tolbutamide, an oral hypoglycemic agent

Anti-inflammatory activity of coldenia procumbens linn

Anti-inflammatory activity of the ethanolic extract of the aerial parts of Coldenia procumbens Linn. was studied in wister rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract [150 mg/kg, p.o.,] produced the inhibition of carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction on the pleural exudates as well as reduction on the granuloma weight in the cotton pellet granuloma method. The results indicated that the ethanolic extract produced significant [P<0.001] anti-inflammatory activity when compared with the standard and untreated control