Superficial bladder tumour recurrence on first check cystoscopy after transurethral resection

To determine the frequency of recurrence of Superficial Transitional Cell Carcinoma on first check cystoscopy after TURBT in six months at the Institute of Kidney Diseases Peshawar. All adult male and female patients with superficial transitional cell carcinoma of urinary bladder were evaluated and resection of the tumour was done and tissue sent for histopathology. Three months after resection, the patients were followed up by cystoscopy and findings noted. Recurrent growth, if present, was resected and sent for histopathology. All the above information were recorded and entered into a structured proforma. The data were analyzed through SPSS version 14 and results were presented in the form of tables and graphs. Our study included 41 patients. 33 [80.5%] were males and 8 [19.5%] females. The age rangedfrom 28 to 85 years with a mean of 59.22 +/- 11.47 years. The presenting T-stage was pTa in 11 [26.8%] patients and pT1 in 30 [73.2%] patients. The presenting histological grade was G-I in 16 [39%], G-II in10 [24.4%] and G-III in 15 [36.6%] patients. On first check cystoscopy, 28 [68.3%] patients showed recurrence while the rest, i.e. 13 [31.7%], showed disease free status. Out of 28 cases with recurrence, 2[4.9%] showed pTa and 26 [63.4%] showed pT1. The recurrence of histological G-I, G-II and G-III were 5, 8 and 15 respectively. Recurrence of superficial TCC at first check cystoscopy is high and has a predictive value for future recurrence of the disease

Bilateral orchiectomy with or without flutamide for advanced carcinoma prostate

To assess the effects of flutamide in patients suffering from advanced carcinoma of the prostate who underwent bilateral orchiectomy. Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar, from March 2008 to July 2009. A total of 100 patients having advanced carcinoma prostate who had undergone bilateral orchiectomy were divided into two groups .Group A consisted of 50 patients who were treated with flutamide while group B having 50 patients received placebo. Relief of bone pain was more in group A than B. No significant difference was seen in the occurrence of adverse effects like nausea, vomiting, hot flashes and anemia between the groups. Eight patients in each group were lost to follow up. The benefit of combined androgen blockade was better in relief of bone pain

Symptomatic complications of ureteric stents

To calculate the frequencies of symptomatic complications of pigtail ureteral stents and to determine the effect of stent duration on symptomatic complications. All s tented adult patients [PTFE Coated Cook_ 6 Fr Double J Stent] presenting at the Institute of Kidney Diseases Hayatabad Peshawar were evaluated by history, examination, urine analysis and cultures, X-ray KUB and ultrasound KUB. SPSS version 11.0 was used for the data entry and analysis. Results are presented in the form of tables. Out of 100 patients, 68% were males and 32% females. Stent indications included stone surgery in 14% of cases, prior to extracorporeal shockwave lithotripsy [ESWL] in 36%, ureteric obstruction in 36%, pyeloplasty in 10%, and anuria in 4% of cases. Complications at 2 and 4 weeks were hematuria in 52% and 40% of cases, flank pain in 48% and 58%, frequency of micturation in 66% and 78%, dysuria in 72% and 80%, urgency in 60% and 72% and suprapubic pain in 42% and 50% of cases respectively. Ureteric s tenting is a life saving procedure but associated with significant morbidity. It's unnecessary and prolonged use should be avoided