A Study for the Anatomic Feature of Asian Tribes: In View Point of the Golden Ratio and Beauty / 체질인류학회지

We observed and measured the structures showing the golden ratio in human body. Southeast Asian tribes, Aka and Lahu who live in Thailand, Miyanmar and China mountain areas and Koreans were examined by means of facial photography. The pictures of lateral facial view were taken by the fixed method. Then the length and width of auricles were measured by Phi-matrix software (version 1.1) on the scanned images. Helix ratio were also obtained by the same method. As a results, the ratio of the ear of Southeast Asian tribes showed the golden ratio and the racial and the individual differences were noticed a little.

Types of Calcaneal Articular Facets of the Talus in Korean / 체질인류학회지

Tali are one of the essential components for weight bearing and play an important role in the foot action. The three calcaneal articular facets of the talus are believed to have diverse morphological variations. However, so far, analysis of the articular facets has not been performed in Korean. In the present study, we classified calcaneal articular facets of the talus and measured several parameters of this bone in Korean adults. Seventy six dry tali (male, 47; female, 29; right, 38; left 38) obtained from forty six (male, 28; female, 18) Korean adult cadavers were used for the investigation. The average age of the cadavers was 64-year-old. Types of calcaneal articular facets of the talus were classified as follows: Type A, a type with three separated facets; Type B, types in which anterior and middle facets are connected, but distinguished by a ridge. Type B was subdivided into B1 (having a notch that separates the two facets partially) and B2 (without a definite notch, thus the two facets appear to be continuous smoothly); Type C, a type with combined anterior and middle facets. Type B was found to be the most common type (60.5%), and the incidence of its subtype B1 (28.9%) and B2 (31.6%) was similar to each other. Type C was noted in 30.3% of the cases, and type A was ranked the lowest (9.3%). Compared to the opposite gender, type C occurred more frequently in males, while type B1 was more prevalent in females. The length of the talus was somewhat longer in males (55.9 mm) than in females (52.8 mm). However, there was no difference between the two sexes in the width of the talus. We could confirm that morphology of calcaneal articular facets of the talus is different between males and females. Also, our results indicate that characteristics of the facets of Korean differ from those of other races. The characteristics of calcaneal articular facets of the talus disclosed by the present study may provide valuable information for the understanding of motor mechanics of the foot in Korean.

Effect of Thiazolidinediones Administration on Neurochemical Composition of MPG Neurons Related to Erection in OLETF Rat / 대한해부학회지

The main transmitter substance mediating erection is the nitric oxide released from the vascular endothelial cells of corpus cavernosum and from the nonadrenergic, noncholinergic nerve endings. In addition, some neurotransmitters, such as acetylcholine or vasoactive intestinal polypeptide (VIP), have been reported to play an important role in mediating the erection. Thus, autonomic neuropathy may cause erectile dysfunction, and in reality, it occurs frequently in individuals with diabetes mellitus (DM), in which polyneuropathy, including both peripheral somatic sensorimotor neuropathy and autonomic neuropathy, develops usually. Thiazolidinedione (TZD) is an insulin-sensitizing agent used for the treatment of type 2 DM with insulin resistance, and has been reported to ameliorate nephropathy, decrease plasma glucose level and reduce blood pressure. However, the effect of this drug on the neuropathy related to erectile dysfunction has never been proved. In the present study, to evaluate the effect of TZDs on the neuropathy concerned with erectile dysfunction, we examined neurochemical changes of major pelvic ganglion (MPG) neurons in Otsuka Long Evans Tokushima Fatty (OLETF) rats, genetic models with non-insulin-dependent DM, after TZDs (pioglitazone and rosiglitazone) treatment. Age-matched nondiabetic Long Evans Tokushima Otsuka (LETO) rats were used as controls. Nitric oxide synthase (NOS), tyrosine hydroxylase (TH), VIP, and neuropeptide Y (NPY) contents were measured in MPG neurons of LETO, OLETF and pioglitazone- or rosiglitazone-treated OLETF rats by morphometry. Compared to the corresponding LETO group, number of TH-, NOS- and VIP-immunoreactive (ir) neurons decreased, while that of NPY-ir neurons, which modulate noradrenergic vasoconstriction of penile arteries, increased in the MPG of the OLETF group. After administration of pioglitazone- or rosiglitazone to OLETF rats for 23 weeks, these neurochemical changes were recovered to the control levels of the LETO group, although some variations were accompanied. These results suggest that TZDs treatment may be helpful for the treatment of autonomic neuropathy concerned with erectile dysfunction.

Analysis of Digital Media and Image Delivery System of Human Anatomic Dissection for Medical Students and Clinicians / 체질인류학회지

In the traditional cadaver dissection course, it is hard to demonstrate dissection skills to all the medical students because of limitations such as the high ratio of students to instructors and the lack of facilities. To overcome these limitations, we developed a digital anatomy dissection course. Through this system, it was possible to perform effective instruction of anatomic dissection. This method could provide the appropriate teaching in a short period of time. Furthermore, students can review the dissection course on digital files saved on a CD-ROM. Clinical cadaveric workshops can be provided by this method not only for students but also for continuing medical education for clinicians.

Effects of Prenatal Stress and Restraint Stress on Amygdala Complex of the Rat: II. Effects on the Astrocytic Cell Processes / 체질인류학회지

The hypothesis that adverse experience alters the balance of neurotransmitters in the amygdala rendering it hyperresponsive to stress was examined in the present study. Since astrocytes regulate the brain's neurochemical milieu by uptaking neurotransmitters, we have examined these cells in the amygdala of prenatally stressed rats, a model of pathological anxiety. Here we examined morphometric changes on the cell bodies of astrocytes in the amygdala induced by prenatal stress and restraint stress. For this purpose, rats were classified into 4 groups; control group (CON), only restraint stressed (starting on P90 for 3 days) group (CONR), prenatally stressed group (PNS), and prenatally and restraint (on P90 for 3 days) stressed group (PNSR). Astrocytes stained with GFAP immunohistochemistry were counter stained with methylene blue/azure II and were examined using the Neurolucida. The present study showed that prenatal and restraint stress caused the significant increase in the total number and length of the amygdaloid astrocytic processes. In conclusion, astrocytes show structural indices of activation with stress.

Immunohistochemical Changes of Nestin, BrdU, and GFAP in the Cells of Rat Spinal Ependymal Zone According to Their Developmental Stages / 대한해부학회지

Recently, there has been considerable attention focused on the multipotent progenitor cells existing in ependymal and subependymal layer. However, almost all results have been derived from brain or injured CNS researches. So, the studies on the developmental characteristics of intact spinal ependymal layer have been relatively ignored. In the present study, we labeled rat spinal cord with nestin, bromodeoxyuridine (BrdU), and glial fibrillary acidic protein (GFAP) antibodies in order to track the differentiation and proliferative capacity of rat ependymal layer cells according to their developmental stages. At embryonic day 14 (E14), a number of cells in the spinal ependymal layer, especially constituting the alar and basal plates, showed extensive nestin immunoreactivities (ir). They also showed active proliferative capacities, because many nuclei of nestin-ir cells were also BrdU-ir. From postnatal day 0 (P0), nestin-ir cells were almost completely disappeared, and from P7, no nestin-ir cells could be detected. However, BrdU-ir nuclei continued to be identified until P14. These results suggested that the cells in the spinal ependymal layer retain their proliferative capacity until later stage of development. On the other hand, no GFAP-ir cells could be identified in the ependymal layer in our experimental period.

Differential Activation of Microglia in the Substantia Nigra and Lesioned Site Following Medial Forebrain Bundle Transection / 대한해부학회지

Medial forebrain bundle (MFB) transmits the nigrostriatal dopaminergic (DA) axons, and previously we reported that transection of the MFB causes apotosis-like neurodegeneration of nigral DA neurons. On the other hand, it is likely to occur necrosis at the lesioned site where MFB is cut, due to direct mechanical transection of the brain tissue. To clarify the pathological dynamics of microglia reacting to the two different types of neuronal cell death, immunophenotypic and morphological features of microglia were compared and analyzed in the substantia nigra (SN) and lesioned site of the MFB axotomized rat brain. OX42 (mouse anti-rat CD 11b; pan-microglia marker), ED1 (mouse anti-rat lysosomal enzyme; phagocytic marker), and OX6 (mouse anti-rat MHC II) were used as primary antibodies for immunohistochemical localization of microglia, ED2 (mouse anti-rat macrophage) for macrophages, and anti-tyrosine hydro-xylase (TH) antibody for DA neurons. Quite numerous activated microglia with strong OX42 immunoreactivity were found in the SN at 1 day post-lesion (dpl), but most of them were ED1-and OX6-negative except only a few which were ED1-positive. This phenomenon was thought to be related with the stage of alert, the first step of microglial activation. It could be presumed that microglial phagocytosis may precede MHC II expression, because ED1-positive microglia appeared from 1 dpl while OX6-positive ones from 3 dpl. Number of activated microglia showing strong ED1, OX6 and OX42 immunoreactivity increased significantly by 7 ~14 dpl, and they specifically stick to various parts of dendrites and somas of TH-immunoreactive neurons of the SN. The phagocytic microglia of the SN maintained ramified form although they retained enlarged soma and shortened, thickened processes. The lesioned site was surrounded by numerous microglia showing strong OX42 and ED1 immunoreactivity as early as 1 dpl, indicating that microglial phagocytosis starts earlier in the lesioned site than in the SN. OX42-positive microglia of the lesioned site were ED2-negative, and showed amoeboid morphology already from 1 dpl. The amoeboid microglia became to be enlarged in their soma size by 3 dpl, and fused each other to form clumps within the necrotic zone by 5 ~7 dpl. The entire necrotic zone was completely filled with microglia of obscure outline with strong OX42 and ED1 immuno-reactivity. However, the majority of amoeboid microglia of the lesioned site were OX6-negative except a few. These results clearly demonstrate that activated microglia reacting to apoptotic neurodegeneration show different pathodynamic characteristics in terms of immunological phenotypes and morphology from those reacting to necrotic, mechanical lesion.

Neuroglial Proliferative Activity Following Medial Forebrain Bundle Axotomy / 대한해부학회지

Changes in morphology, immunophenotypes and proliferative activity of neuroglia are key features in most forms of CNS pathology. We compared proliferative activity of neuroglial cells in response to two different types of brain injury induced by medial forebrain bundle (MFB) axotomy. In the cannula track where acute necrosis occurs due to mechanical lesion caused by cannula inserted to incise the MFB, many BrdU-immunoreactive (ir) cells appeared around the cannula track already at 1 day post-lesion (1 dpl). Their number significantly increased by 7 dpl and then decreased, but considerable number of BrdU-ir cells was still found at 14 dpl. Some of the BrdU-ir cells were double-labeled with either OX-42 or GFAP. This finding suggests that both microglia and astrocytes are activated and proliferate immediately after the mechanical damage, and the proliferative activity is maintained in a considerable number of these cells by 14 dpl. In general, the main cell type showing BrdU immunoreactivity was amoeboid microglia within the necrotic zone immediately surrounding the cannula track, and was astrocytes in the periphery of the necrotic zone more or less apart from the cannula track. Previously, we reported that MFB axotomy induces apoptosis of dopaminergic (DA) neurons in the substantia nigra (SN). In the SN where axotomized DA neurons undergo apoptosis, only a few BrdU-ir cells were found at 1 dpl. Their number increased gradually from 3 dpl and peaked at 7 dpl, then significantly reduced at 14 dpl. Most of them were double-labeled with OX -42-positive ramified microglia but not with GFAP. This data indicates that microglia but not astrocyte are the cell type that proliferate in response to apoptotic neuronal cell death, and their morphology and proliferative activity are different from those observed in the cannula track. Meanwhile, in the both cannula track and SN, some BrdU-ir cells were thought to be neither GFAP-positive nor OX-42-positive, and thus they were presumed to be infiltrated peripheral immune cells. These results demonstrate that different types of neuronal cell death are accompanied with different neurogilal proliferative activities.

Tortuosity of Vertebral Artery between the Atlas and the Axis / 체질인류학회지

This study was performed to investigate the anatomical features of vertebral artery between the atlas and the axis. For this, we examined four angles (angle I, angle II, angle III and angle IV) to identify tortuosity of vertebral artery and diameter between the atlas and the axis. Materials used in this study were 93 vertebral arteries obtained from 48 adult Korean cadavers (34 males, 14 females) ranging from 18 to 90 years in age. On the anterior view, the vertebral artery relatively ascended vertically from C6 to the axis and then laterally passed through the foramen transversarium (FT) of the axis. The average of this angle I was 83.3 degree. The average of the right and left sides of this angle I were 84.7 degree and 82.0 degree, respectively. The average of angle I (95.4 degree) in female was larger than that (80.5 degree) of male. The artery passed through the FT of the axis turned to the superior direction. The average of this angle II was 95.9 degree. The right and left sides of the angle II were 97.8 degree and 93.8 degree, respectively. As the angle I, the average of angle II (110.6 degree) in female was larger than that of angle II (93.1 degree) in male. On the lateral view, the vertebral artery relatively ascended vertically from C6 to the axis and then posteriorly passed through the FT of the axis. The average of this angle III was 71.3 degree. The artery passed through the FT of the axis turned to the superior direction. The average of this angle IV was 87.3 degree. In angle III and angle IV, the average of angle in female were larger than that of male. These results show that female has greater tortuosity than male. The average diameter of the vertebral artery was 3.7 mm and the average diameter of right and left are 3.5 mm and 4.0 mm, respectively. In 76% of the total, left vertebral artery diameter was larger than that of the right.

Statistic Approach for Sex Differentiation of Dried Korean Pelvic Bones / 체질인류학회지

Pelvic bone is the major bone which has the quite different features between male and female. And these features are well described in almost all gross anatomy textbooks. The parameters which are used to sex determination are related with the those of obstetrics. To suggest the most significant parameters for sex discrimination with the bones, we have selected the frequently mentioned 21 metric fields of non -pathologic Korean pelvic bones, whose sexes were already confirmed (M 40, F 19). For measuring these metric parameters, the statistic procedure (descriptive statistics and discriminant analysis, group analysis) was performed (SAS PC version 6.12). The parameters showing more than 80% of discriminating probability are the acetabular length (Martin #22) and the pubic angle (Martin #16). The parameters showing more than 75% of discriminating probability are the transverse diameters of pelvic outlet (Martin #27), the breadth of greater sciatic notch, the ischial length (Martin # 15a), the pelvic breadth (Martin #2), the obturator foramen long length (Martin #20), the obturator foramen short length (Martin #20), and the pelvic height (Martin #1). All the metric parameters could be categorized into 5 groups.

Secular Changes of Cephalic Index in Korean Adults / 체질인류학회지

From the beginning of the twentieth century to the present, human head has been changed from an anteroposteriorly long shape to a short one. This phenomenon is called "brachycephalization" Somatometric data showed the rapid brachycephalization of Korean in twentieth century. The causes of brachycephalizaion have not been yet fully elucidated. Secular trends of head length, head breadth were studied. Height was added for comparison. A sample of 1,568 Korean adults was measured. The cephalic index was calculated and compared with the previous reported data. The head length and head breadth were increased continually during the last hundred years. But the latter was more increased than the former. Therefore, the increase of head breadth has been thought to be the main cause of brachycephalization. The pattern of secular changes of cephalic index of Koreans showed close relation to that in height. These findings were more evident in females than in males.

Group Analysis Using the Metric Measurements of Korean skulls / 체질인류학회지

The metric parameters including Martin's (#41, 43, 44, 45, 46, 51, 52, 53) and non -Martin's parameters (nasion - occipital length, glabella -occipital length, nasion -inion length, glabella -lambda length, basion -nasion length, biauricular breadth, biasterion breadth, porion -bregma height, porion -vertex height, frontal arc, frontal chord, parietal arc, parietal chord, occipital arc, occipital chord, mastoid height, mastoid width, basion -prosthion length, internal palate length, internal palate breadth, external palate length, external palate breadth) were measured on 61 Korean skulls (M47, F14) with cephalometry (GPM Co., Swiss) and calipers (GPM Co., Swiss, Mitutoyo Co, Japan). Using the metric data of 35 parameteres, the statistic procedure (descriptive statistics, t -test, paired t -test, discrimination process, group analysis) was performed. Among those parameters, 28 parameters have the statistic significance in group analysis. The 2 clustering was most appropriate.

Non -metric Traits of Korean Skulls / 체질인류학회지

Thirty -nine non -metric cranial traits of the Korean skulls were investigated and compared with those of eighteen human populations. The Korean have the highest incidence of the accessory infraorbital foramen (18%) of all populations compared. The sutural infraorbital foramen, posterior ethmoidal foramen absent, ear exotosis, temporal ossicle and bregmatic bone were not observed in the Korean samples. The distance analyses (MMD; mean value of divergence) revealed that the Korean are more closely related to the population in Kazach and Mongol than to the population in China and Japan.

A Case Report of Situs Inversus Totalis / 체질인류학회지

A 55 yr -old female patient visited to the OPD of OS department complaining of the lumbago, the radiating pain to right thigh and the swelling of right knee and calf regions. On routine chest and abdominal X -ray and ECG, the dextrocardia was revealed. For further detail examination, Doppler US, lung perfusion scan, MRI images were obtained. As a result, the situs inversus with dextrocardia was confirmed. Other congenital anomalies or diseases were not combined. The patient was cared with conservative treatment of lowback pain via OPD. And she was recovered successfully.

Sex Discrimination with the Metric Measurements of the Korean dried Pelvic Bones by Discriminant Function Analysis / 체질인류학회지

Pelvic bone is the representative bone which has the quite different features discriminating the sex. And these features are well described in almost all gross anatomy textbooks. The parameters which are used to sex determination are relating to the those of obstetrics. To suggest the most significant parameters for sex discrimination with the bones, we have selected the frequently mentioned 21 metric fields of non-pathologic Korean pelvic bones, which sexes were already confirmed (M: 40, F : 19). Measuring theses metric measurements, the statistic procedure (descriptive statistics and discriminant analysis) were performed (SASPC version 6.11). The parameters showing more than 80% of discriminating probability are the acetabular length (Martin No. 22) and the pubic angle(Martin No. 16). The parameters showing more than 75% of discriminating probability are the transverse diameters of pelvic outlet (Martin No. 27), the breadth of greater sciatic notch, the ischiatic length (Martin No. 15a), the pelvic breadth (Martin No. 2), the obturator foramen long length (Martin No. 20), the obturator foramen short length (Martin No. 20) and the pelvic height (Martin No. 1).

Anterior clinoid process and optic strut in Koreans

The anterior clinoid process and the optic strut are often removed during operation on the anterior part of the cavernous sinus. Therefore it is important for neurosurgeons to verify their dimensions and variations. The purpose of this study was to investigate the dimension and the variation of the anterior clinoid process and to describe the locational variation of the optic strut. Seventy-three skulls of Korean adults were used. The average length, basal width and thickness of the anterior clinoid process were 9.18 +/- 1.55, 9.63 +/- 1.49 and 5.32 +/- 1.07 mm, respectively. The average thickness of the optic strut was 2.9 +/- 1.15 mm and it was commonly attached to anterior two-fifths of the anterior clinoid process. The complete caroticoclinoid canal was observed in 4.1%, however it was incomplete in 11.6%. The incidence of a caroticoclinoid canal in Koreans was relatively low compared with other races.

Correlation between the postmortem stature and the dried limb-bone lengths of Korean adult males

The postmortem stature was measured in 57 Korean adult males (age range: 20-86 years old, mean: 52.3 years old) in supine position. After dissection of the corpses, we measured the maximum length of the remaining limb-bones (humerus, radius, ulna, femur, tibia and fibula). The correlation coefficients between the stature and each limb-bone length were calculated. Simple regression equations for estimating stature from each limb-bone length and multiple regression equations from the combination of limb-bone lengths were also obtained.

Study on the Korean adult cranial capacity

Cranial capacity was measured in Korean adult skulls. The cavity was filled with rice seeds and the volume of the seeds were measured in a graduated cylinder. The results were 1470 +/- 107 (mean +/- standard deviation) in male and 1317 +/- 117 cc in female skulls. These values were in good accordance with those previously reported. In addition, regression formulae were obtained with the product of the length, breadth, and height of the skull as an independent parameter and the measured capacity as a dependent one. With known external measurements, the expected cranial capacity was as follows: when using baso-bregmatic height, male: capacity = 307.5 + 333 x 10(-6) x (length.breadth.baso-bregmatic height) female: capacity = -12.0 + 435 x 10(-6) x (length.breadth.baso-bregmatic height) and, when using auriculo-bregmatic height, male: capacity = 214.6 + 429 x 10(-6) x (length.breadth.auriculo-bregmatic height) female: capacity = 131.6 + 461 x 10(-6) x (length.breadth.auriculo-bregmatic height).

Morphologic Characteristics of Finger and Palm Prints of the Akha and Lahu in Northern Thailand / 체질인류학회지

In this study of the physical anthropological characteristics of the Akha and Lahu in northern Thailand, whose customs are similar to the Koreans, the authors examined the finger and palm prints of the Akha (male 107, female 114) and Lahu (male 92, female 101) using qualitative methods, and compared them with those of various ethnic groups including Koreans. The results were as follows : The whorl types (Akha 57.7%, Lahu 58.1%) were the most common finger prints, followed by ulnar loop types (Akha 39.7%, Lahu 38.7%), arch types (Akha 2.6%, Lahu 2.8%), and radial loop types (Akha 1.7%, Lahu 1.2%). Of the palm print types, 9-7-5 (Akha 32.7%, Lahu 21.3%) and 7-5-5(Akha 25.4%, Lahu 21.3%) were most common, followed by 11-O-7 (Akha 2.0%, Lahu 11.3%), 9-O-5 (Akha 1.5%, Lahu 10.0%), 11-9-7 (Akha 6.0%, Lahu 5.7%), 7-5-4 (Akha 7.0%, Lahu 2.2%). The finger and palm print patterns of the Akha and Lahu did not correspond closely to the patterns of those classified as White, Negro, or Oriental, although they were closest to the patterns of the latter, particularly Chinese (rather than Korean or Japanese).

Re-evaluation of the Orbital Dimensions in Modern Korean Adult Skulls / 체질인류학회지

This article describes the normal range of orbital linear dimensions (eq. orbital breadths, orbital height, orbital depth, interorbital breadths and biorbital breadth) and orbital indicies. One hundred and eighty-seven Korean skulls from grown-up individuals are studied with analysis for the purpose of evaluating anthropometric characteristics of Korean orbits. The results are compared to previously published data for modern Korean skulls. The width of the orbit is larger on the right side than the left and sexual difference was also shown. On the other hand, the heights of both orbits are much the same. Consequently, there is a slight tendency that chamaeconch is met with more frequently on the right side, whilst hypsiconch on the left side. The orbital depth is larger on the right side, however, depth index did not show any side difference. There are sexual differences on the biorbital breadth and upper facial breadth but not on the interorbital breadth on the basis of dacryon. These results represent the asymmetry of Korean orbit and that measurement on both sides must be necessary for anthropological comparison.