Idiopathic central precocious puberty: A case report / Philippine Journal of Obstetrics and Gynecology

Central precocious puberty is characterized by early pubertal changes, acceleration of growth velocity, and rapid bone maturation. It is a relatively rare disorder, with an incidence rate of about 1:5000-1:10000 individuals in the general population; it is more frequent in girls than in boys. This is a case of a 7 year-old female complaining of onset of menstruation. Physical examination revealed advanced pubertal changes of Tanner stage 4-5 for breast and stage 3 for pubis. Diagnostic evaluation revealed well developed internal genitalia, markedly elevated LH levels, advanced bone aging and a normal cranial MRI. Based on clinical and diagnostic evaluations, a diagnosis of idiopathic central precocious puberty was made and the patient was started on GnRha therapy. It is important to initiate therapy early in patients with central precocious puberty so as to prevent compromised adult height and psychosocial embarrasment

Mullerianosis of the urinary bladder: First case report in the Philippines / Philippine Journal of Obstetrics and Gynecology

Mullerianosis is a rare, benign, and morphologically complex, tumor-like lesion that consists of an organoid structure with normal Müllerian tissue. The diagnosis requires the presence of at least two of the three mullerian tissues: endometriosis, endosalpingiosis, and endocervicosis. There are only less than twenty (20) cases reported in literature. At present there is no published case report of mullerianosis here in the Philippines. This is a case report of a 30-year old Filipino woman who presented predominantly with lower urinary tract symptoms of severe dysuria, hematuria, and lumbar pain and was evaluated for a urologic problem secondary to a posterior bladder mass. Subsequent evaluations revealed the diagnosis of mullerianosis. This is where the interest in mullerianosis sets, its potential to mimic a neoplastic lesion of the urinary tract from clinical and diagnostic viewpoints. The clinical importance to diagnose this case correctly is of grave importance for appropriate management.

A 5 year retrospective review of pregnancy loss among women with polycystic ovarian morphology

BACKGROUND: Polycystic ovarian morphology is the most common ultrasound abnormality among women with recurrent pregnancy loss and as such, its presence has been postulated to have a relationship with a high rate of miscarriage among women conceiving spontaneously. Objective: The study aimed to determine the prevalence of pregnancy loss among women who have polycystic ovaries on ultrasound, at a tertiary hospital from January 2010 to December 2015.MATERIALS AND METHODS: A cross-sectional investigation involving a retrospective review of hospital records of 377 women who were diagnosed with polycystic ovaries on transvaginal ultrasound was performed. Their pregnancy outcomes were followed up by retrieving their medical charts at the outpatient department, consultants' clinics and the medical records section. Approval from the Independent Ethics Committee and Center for Clinical Epidemiology and Biostatistics was obtained.RESULTS: Of the 377 women with polycystic ovarian morphology, 280 (74.27%) met the 2003 Rotterdam criteria for polycystic ovary syndrome. The prevalence of pregnancy loss was 40.23%, while the live birth rate was 59.77% among the 377 women with polycystic ovaries on ultrasound. The majority of pregnancy loss occurred in the first trimester of pregnancy with a mean age of gestation of 8.9 ± 4.8 weeksCONCLUSION: The prevelance of pregnancy loss among women with polycystic ovarian morphology was 40.23%