Preoperative subconjunctival injection of mitomycin C versus intraoperative topical application as an adjunctive treatment for surgical removal of primary pterygium

To compare the efficacy of preoperative local injection of mitomycin C [MMC] to intraoperative application of MMC in the prevention of pterygium recurrence after surgical removal. Seventy eyes of 70 patients with primary pterygia were randomly allocated to two groups. The first group [Group A, 35 eyes] received 0.1 ml of 0.15 mg/ml of subconjunctival MMC injected into the head of the pterygium 24 h before surgical excision with the bare sclera technique. The second group [Group B 35 eyes] underwent surgical removal with the bare sclera technique with intraoperative application of MMC [0.15 mg/ml] over bare sclera for 3 min. The study was performed between March 2007 and December 2008, and follow up was performed for 1 year postoperatively. Differences between frequencies in both groups were compared by the Chi-square test or Fisher exact test. Differences between means in both groups were compared by Student's t-test. P < 0.05 was considered significant. The rate of pterygium recurrence was 5.70% in Group A and 8.57% in Group B at 1 year postoperatively [P>0.05]. Postoperatively, scleral thinning occurred in one eye in each group that resolved by 5 months postoperatively. No serious postoperative complications occurred in either group. Preoperative local injection of 0.15 mg/ml MMC is as effective as intraoperative topical application of 0.15 mg/ml MMC for preventing pterygium recurrence after surgical removal

Ropivacaine and hyaluronidase versus ropivacaine and lidocaine for peribulbar anaesthesia in cataract surgery with phacoemulsification

Comparison between the anaesthestic efficacy of 0.75% ropivacaine and 50UI/ ml hyaluronidase with 0.75% ropivacaine and 2% lidocaine during peribulbar anaesthesia for cataract surgery. The study is a double blind randomized clinical trial. Thirty physical status ASA asterisk I-Ill patients were randomly allocated to two groups. Ropivacaine/ hyaluronidase group received 5ml of 0.75% ropivacaine plus 50 IU ml[-1] hyalurnoidase [RH group], and ropivacaine/ lidocaine group received 5ml of equal parts of 0.75% ropivacaine and 2% lidocaine [RL group]. Speed of onset and quality of motor blockade were assessed using ocular and eyelid movement scores, and sensory blockade was assessed by the three- point scoring system. Surgical and patients satisfaction, and incidence of complications were recorded. The groups showed no difference in the rate of onset or degree of akinesis achieved. Akinesia scores of

Measurement of retinal nerve fiber layer thickness in diabetic patients using optical coherence tomography [OCT]

The concern of this study is to measure the retinal nerve fiber layer thickness [RNFLT] in diabetic patients with different stages of diabetic retinopathy. Descriptive study. Sixty eyes of 48 of diabetic patients [type I and type II] attending the ophthalmology department, faculty of medicine, Suez canal university, a twenty aged matched normal subject was taken as control for RNFLT measurement by optical coherent tomography OCT. Patients were divided into three groups each consists of 20 eyes. Group 1 with mild and moderate background diabetic retinopathy [BDR], group 2 severe and very severe BDR and group 3 proliferative diabetic retinopathy [PDR]. The results of RNFLT in all stages of diabetic retinopathy indicate a marked loss mainly in the inferior and superior quadrants copared to the control group especially in all groups. Diabetes decrease RNFLT in all stages of diabetic retinopathy especially in the superior and inferior quadrants