Surface electromyography of lower limb muscles in healthy middle-aged and old women during stair ascent and descent / 中国康复理论与实践

ObjectiveTo observe the lower limb muscle activation strategy of healthy middle-aged and old women during stair ascent and descent with surface electromyography. MethodsFrom August, 2021 to February, 2022, 20 healthy middle-aged and old women were measured the surface electromyography root mean square (RMS) and integrated electromyography (iEMG) of bilateral vastus lateral, rectus femoris, vastus medialis, biceps femoris and semitendinosus during stair ascent and descent, and co-contraction ratio was calculated. ResultsDuring stair ascent, the RMS of bilateral vastus lateral, rectus femoris and vastus medialis was higher at starting stage than at following stage (|t| > 6.650, P < 0.001), while the RMS of biceps femoris and semitendinosus was lower (t > 3.559, P < 0.01); and the co-contraction ratio of hamstrings/quadriceps was lower at starting stage than at following stage (t > 8.185, P < 0.001). During stair descent, the RMS of bilateral vastus lateral, vastus medialis, biceps femoris and semitendinosus was higher at following stage than at starting stage (t > 2.345, P < 0.05), as well as the co-contraction ratio of hamstrings/quadriceps (t > 2.405, P < 0.05). ConclusionThe activities of the muscles around the knees are almost symmetrical during stair ascent and descent for healthy middle-aged and old women. The activation and co-contraction ratio of quadriceps and hamstring are various at starting/following stages.

Tactile vibration feedback training can improve the balance and walking of stroke survivors / 中华物理医学与康复杂志

Objective:To observe any effect of tactile vibration feedback training on the balance and wal-king ability of stroke survivors.Methods:Fifty stroke survivors who met the selection criteria were randomly divided into a control group ( n=25) and an observation group ( n=25). In addition to conventional exercise training, neuromuscular electrical stimulation and biofeedback therapy, the control group underwent one hour of walking training daily, 5 days a week for 6 weeks, while the observation group received tactile vibration feedback training with the same timetable. Before and after the treatment, lower limb motor function was evaluated using the Berg Balance Scale (BBS), the Timed Up and Go (TUG) test and the Fugl-Meyer lower extremity assessment (FMA-LE). A Gaitrite analyzer recorded the gait parameters of the two groups. The step length on the unaffected side was recorded and the duration of the single support phase was compared between the affected and healthy sides. Results:Before the treatment, there was no significant difference between the two groups in average step length on the unaffected side or in the difference in duration of the single support phase between the affected and healthy sides. The average BBS scores, TUG test times and FMA-LE scores also were not significantly different. After the treatment all of those indicators were significantly better in the treatment group, on average.Conclusions:Tactile vibration feedback training can significantly improve the balance and walking ability of stroke survivors during the recovery period, and lower their risks of falling.

Clinical effects of ultrasound-guided intra-articular and coracohumeral ligament injections on frozen shoulder in the elderly / 中华老年医学杂志

Objective:To compare the clinical effects of ultrasound-guided intra-articular and coracohumeral ligament glucocorticoid injections versus ultrasound-guided intra-articular glucocorticoid injections alone on frozen shoulder in the elderly.Methods:A total of 44 patients with frozen shoulder admitted to the rehabilitation department of the Affiliated Hospital of Sichuan Nursing Vocational College from September 2019 to June 2020 were enrolled.They were randomly divided into the experimental group and the control group, with 22 patients in each group.The experimental group received two consecutive ultrasound-guided intra-articular injections and two coracohumeral ligament injections, while the control group received two consecutive ultrasound-guided intra-articular injections.The shoulder's passive range-of-motion(PROM), the 11-point numeric rating scale(NRS)as well as the Shoulder Pain and Disability Index(SPADI)were conducted before treatment, 1 week after the first treatment(1 week), 1 week after the second treatment(2 weeks)and 10 weeks after the second treatment(12 weeks).Results:There was no significant difference in baseline characteristics between the two groups(all P>0.05). Flexion, abduction, extension and external rotation increased whereas NRS and SPADI decreased after treatment, compared with pre-treatment in the experimental group( F=11.341, 20.965, 20.403, 32.470, 82.970 and 102.154, all P<0.05)and in the control group( F=7.012, 8.937, 23.265, 31.966, 52.500 and 41.356, all P<0.05). Compared with the control group, extension( t=0.365, 0.143 and 0.236, all P<0.05)and external rotation( t=0.205, 0.620 and 2.751, all P<0.05)increased at 1, 2 and 12 weeks after treatment.SPADI scores were lower in the experimental group than in the control group at 12 weeks after treatment( t=2.063, P=0.045). There was no significant difference in NRS, flexion or abduction between the two groups at any time point after treatment(all P>0.05). No serious adverse reactions occurred during treatment in either group. Conclusions:Both ultrasound-guided intra-articular injections plus coracohumeral ligament injections and ultrasound-guided intra-articular injections can effectively alleviate pain and improve function in elderly patients with frozen shoulder, but the former has better effects on extension.For patients with clear restricted extension and external rotation, ultrasound-guided intra-articular injections combined with coracohumeral ligament injections may achieve better clinical effects.

Electro-acupuncture regulates the expression of the silence regulator homolog 1 and p53 tumor suppressor genes in the chondrocytes of osteoarthritic knees / 中华物理医学与康复杂志

Objective:To investigate any effect of electro-acupuncture stimulation on the expression of the silence regulator homolog 1 (SIRT1) and p53 tumor suppressor genes in chondrocytes of persons with osteoarthritis (OA).Methods:Thirty-six experimental rabbits were randomly divided into a control group, a model group and an electro-acupuncture group, each of 12. One knee of each rabbit in the model and electro-acupuncture groups was fixed for 6 weeks to induce OA, while the control group was not given any intervention. The rabbits in the electro-acupuncture group were then treated with electro-acupuncture for 16 days; the model group rabbits were fixed to the treatment table but were not given electro-acupuncture. At the end of the experiment, the articular cartilage was hematoxylin-eosin (HE) stained for microscopic examination and Mankin scoring. The chondrocytes′ gray values after immunohistochemical staining allowed determination of the SIRT1 and p53 expression levels.Results:The average histopathological grade, Mankin score and stained Mankin score of the electro-acupuncture group were all superior to the model group′s averages. SIRT1 and p53 expression were detected in all three groups, but the SIRT1 gray value of the model group was significantly higher than the other two groups′ averages. The average p53 gray value in the model group was significantly lower.Conclusions:Electro-acupuncture can effectively alleviate the symptoms of knee OA, perhaps by up-regulating SIRT1 expression in the cartilage, inhibiting apoptosis of articular chondrocytes and generally promoting cell regeneration.

Early mirror therapy and the functional recovery of hemiparetic stroke survivors / 中华物理医学与康复杂志

Objective To investigate the effect of early intervention with mirror therapy on hemiparetie survivors of ischemic stroke.Methods Thirty-six hemiplegic patients within one month after a stroke were randomly divided into a mirror therapy group (MT group,n=18) and a routine rehabilitation control group (RRC group,n=18).The participants in the MT group received MT for 45 min/d,5 d/wk for 3 weeks in addition to conventional stroke rehabilitation.Those in the RRC group received exercise therapy at the same frequency without the mirror protocol.The Fugl-Meyer assessment (FMA),Wolf motor function test (WMFT),functional ambulation category scale (FAC),Brunnstrom stages of motor recovery,and the modified Ashworth scale (MAS) were used to assess changes in the upper limb,gross hand dexterity and lower limb recovery before and right after the interventions,as well as one and two months after the treatment.Results Significant improvement was observed in the limb function of both groups after the treatment.Compared with the RRC group,there was significantly greater improvement observed in the MT group.This was true of the FMA ratings at all time points,the average WMFT scores one and two months after the intervention,the FAC ratings two months after the intervention,and the Brunnstrom stages at both one and two months after the intervention.However,no significant difference between the two groups in terms of the average MAS scores was observed at any time point.Conclusion Early intervention with MT can significantly accelerate the recovery of a paretic upper limb aud improve walking ability after stroke.Such intervention is worthy of promotion and application in clinical practice.

Mirror therapy improves the upper limb function of hemiparetic stroke survivors: A meta-analysis / 中华物理医学与康复杂志

Objective To evaluate systematically the efficacy of mirror therapy for improving the upper limb function, daily life and pain of stroke survivors. Methods The PubMed, EBSCO, Web of Science, Ovid, Co-chrane Library, Open Gray, China Biological Medicine, China National Knowledge Infrastructure, GoogleScholar, VIP and Wan Fang Data databases were searched for reports of randomized and controlled trials ( RCTs) of mirror therapy for improving the upper limb function of stroke survivors. Only papers published before December 2015 were surveyed. The relevant references of the primary studies were also searched. The literature screening, data extraction and assessments were conducted by two reviewers independently. The meta-analysis was performed using version 5.2 of the RevMan software. Results A total of 22 RCTs involving 823 patients were discovered, some not dealing with mirror therapy. Comparing the studies with and without visual feedback, there were significant differences in upper limb motor function as measured by the Fugl-Meyer, ARAT and Brunnstrom instruments. The average Barthel indexes and visual analogue scale were also significantly different. Conclusion Mirror therapy can improve upper limb function and ability in the activities of daily living, and also relieve pain among stroke survivors to some degree, though its long-term efficacy is still unclear. Large-sample, multi-center, high-quality RCTs are required to verify these conclusions.

Electroacupuncture for chronic pain in a model of knee arthritis / 中国组织工程研究

BACKGROUND:Acupuncture has been found to be effective for alleviating low back pain and acute pain due to knee arthritis, but its effect on chronic pain is under discussion. OBJECTIVE:To investigate the mechanism underlying electroacupuncture (EA) alleviating chronic pain in a New Zealand rabbit model of knee arthritis. METHODS:(1) Thirty-two New Zealand rabbits were selected, and the knee osteoarthritis model was established by injecting 4% papain into the knee articular cavity of rabbit's bilateral hind limbs. The model rabbits were randomly divided into four groups (n=8 per group): normal saline plus EA, normal saline plus sham EA, nor-Binaltorphimine (nor-BNI) plus EA, and nor-BNI plus sham EA groups. The dosage of nor-BNI was 1 mg/kg, once daily, for consecutive 3 days. 30-minute EA was given at 2 hours after administration, once daily, until the day the rabbits were killed. Sham EA indicated no given electric current. The behaviors of the lower limbs were evaluated by Basso, Beattie, Bresnahan scores. The rabbits were respectively killed at 1, 3, 5 and 7 days after administration, the spinal cord was separated, and then fixed with formaldehyde. The expression levels of interleukin-17, interleukin-17 receptor A and NR1 in the spinal cord tissues were detected by immunofluorescence. (2) The other 24 New Zealand rabbits were randomly divided into model and control groups (n=12 per group), and the knee osteoarthritis model was established in the former group. Afterwards, the two groups were randomized into two subgroups, followed by given the intrathecal administration of normal saline, or 2 μg interleukin-17 antibody serum dissolvedin 10 μL normal saline, once daily, for consecutive 3 days. The behaviors of the lower limbs were evaluated by Basso, Beattie, Bresnahan scores, and the expression levels of p-NR1 and interleukin-17 receptor were detected by western blot assy. RESULTS AND CONCLUSION:The Basso, Beattie, Bresnahan scores in the nor-BNI plus EA group were significantly increased, while the expression levels of interleukin-17, interleukin-17 receptor A and NR1 in the spinal cord tissues were significantly decreased (P 0.05). After administration of interleukin-17 antibody serum, the Basso, Beattie, Bresnahan scores in the model group was significantly increased, and the expression levels of interleukin-17 and NR1 in the spinal cord tissues were significantly decreased, but still significantly higher than those in the control subgroups (P< 0.05). These results suggest that chronic pain in knee arthritis is the result of an increase in the expression level of NRI induced by interleukin-17. EA can remarkably improve the pain in the model rabbits of knee arthritis by downregulating interleukin-17 in the spinal cord tissues, rather than interleukin-17 receptor.

Clinical effect analysis of Xiaoke-Yuzu decoction on diabetic peripheral neuropathy / 国际中医中药杂志

Objective To observe the clinical effect of Xiaoke-Yuzu decoction on diabetic peripheral neuropathy (DPN). Methods A total of 100 DPN inpatients were recruited and randomly divided into the treatment and control groups. The two groups were both received basic therapy, while the treatment group additionally received Xiaoke-Yuzu decoction. Toronto clinical scores and Chinese medicine symptom scores of both groups were collected to evaluate the clinical effect before and after the therapy. Results The Toronto scores of treatment group were significantly lower than control group after treatment (symptoms score 1.50 ± 0.94 vs. 2.23 ± 1.01, reflection score 3.60 ± 1.77 vs. 4.27 ± 1.72, feeling test score 1.53 ± 0.63 vs. 2.10 ± 0.84,all P<0.05). Meanwhile, the Chinese medicine symptom scores of treatment group were also significantly lower than the control group (main symptom score 1.77 ± 1.17 vs. 3.17 ± 1.82, posterior symptom score 2.23 ± 1.59 vs. 4.27 ± 1.57, the tongue and pulse score 1.83 ± 0.65 vs. 2.47 ± 0.51, all P<0.05). Conclusion Xiaoke-Yuzu decoction plus basic therpy could improve the clinical symptoms of DPN patients.

Observation of Neuromuscular Electrical Stimulation Combined with Kinesitherapy for Brachial Plexus Injury / 中国康复理论与实践

Objective To observe the clinical effect of neuromuscular electrical stimulation combined with kinesitherapy on dysfunction after brachial plexus injury. Methods 60 cases with brachial plexus injury following dysfunction were divided into two groups. The experi-mental group (n=30) was treated with neuromuscular electrical stimulation combined with kinesitherapy. The control group (n=30) was treat-ed with kinesitherapy. Two groups were assessed by the brachial plexus function evaluation standard before and 3 months after the treat-ment. Results Two group all improved 3 months after the treatment (P<0.05), while the experimental group was better than the control group (P<0.01). Conclusion Neuromuscular electrical stimulation combined with kinesitherapy is more effective to improve the function af-ter brachial plexus injury.

Application of Problem-based Learning in Course of Rehabilitation / 中国康复理论与实践

@#Through comparing problem-based learning and lecture-based learning, the PBL teaching can improve the learning interest and self-learning ability of students and also can accomplish the task of teaching better.

Feasibility of constructing artificial cartilage with rabbit mesenchymal stem cells and polyglycolic acid scaffold / 中国组织工程研究

BACKGROUND: Whether choosing a suitable biological scaffold compounding with mesenchymal stem cells (MSCs) can construct an ideal tissue-engineering cartilage or not should be researched further.OBJ ECTIVE: To investigate the feasibility of constructing artificial cartilage by using amplified rabbit MSCs which were inoculated on poly-glycolic acid (PGA).DESIGN: Single sample observation.SETTING: Department of Otolaryngology-Head & Neck Surgery, Affiliated Hospital of Sichuan Luzhou Medical College.MATERIALS: The experiment was carried out in the Luzhou Medical College from October 2004 to October 2005. A total of 8 Japanese large ear rabbits, of both genders, clean grade, aged from 2 to 3 months, weighing 1.5-2.0 kg, were fed in normal temperature and humidity. Poly-glycolic acid was provided by Albany Company, USA.METHODS: Rabbit MSCs were separated, obtained and amplified. In addition, poly-glycolic acid was sheared into pieces with the size of 1 cm × 1 cm × 1 cm and embedded with poly-L-lysine. Amplified MSCs were inoculated on the surface of poly-glycolic acid, and then, they were averagely grown on pre-wet scaffold of poly-glycolic acid according to 4 mL/cm3multi-points spreading style and cultured in vitro for 3 weeks. After the operations mentioned above, samples were regarded as the experimental group. Scaffolds of poly-glycolic acid without MSCs were considered as the control group.Samples in both experimental group and control group were transplanted into abdominal cavity of 4 rabbits, respectively,cultured in vivo for 6-12 weeks, taken out and observed generally. Meanwhile, the samples were fixed with 100 g/L neutrality formaldehyde, cut into sections with the thickness of 5 μm, stained with haematine-eosin (HE) and observed their histomorphological characteristics. Moreover, the samples were stained with alcian blue for observation of glycosaminoglycans formation, with toluidine blue for observation of metachromasia matrix formation, and with immunohistochemical staining for detection of type- Ⅱ collagen expression.MAIN OUTCOME MEASURES: Generally observational results of two kinds ofscaffolds at 6 and 12 weeks after transplanting into experimental rabbits, various staining results and expression of type- Ⅱ collagen.RESULTS: A total of 8 experimental rabbits were involved in the final analysis. ① Generally observational results of two kinds of scaffolds at 6 and 12 weeks after transplanting into experimental rabbits: At 6 weeks after transplanting scaffold into abdominal cavity of rabbits, samples in the experimental group were still coated with greater omentum of abdominal cavity. After clearing greater omentum, three samples were light yellow, smooth and moderate quality; meanwhile, their appearances were coincidence with those before transplantation. However, one sample was gray black and soft quality;meanwhile, it was not able to take shape. Twelve weeks later, appearances of samples in the experimental group were still coincidence with those before transplantation. They were gray white, smooth but hard quality. However, samples in the control group were mostly absorbed at 6 and 12 weeks after transplantation, especially, samples were remarkably absorbed at 12 weeks after transplantation. Any tissue like cartilage did not form in both two durations. ② Various staining results and expression of type- Ⅱ collagen at 6 and 12 weeks after transplanting scaffolds into experimental rabbits: Results of HE staining showed that, at 6 weeks after transplantation, structure of cartilage lacuna-like was started form, and PGA scaffold began to be degraded. In contrast, at 12 weeks postoperatively, some cartilage-like tissue were observed in compound, cartilage lacuna-like structure formed obviously; cells arrayed regularly and geminately existed In cartilage lacuna-like atructure; the smaller cell sizes observed at borders and the bigger ones observed at the center;PGA degraded completely. Results of alcian blue staining showed that, at 6 weeks after transplantation, a partial of regions in tissue were light blue; meanwhile, at 12 weeks after transplantation, matrixes in tissue were mostly blue. This suggested that a lot of glycosaminoglycans were formed. Results of toluidine blue staining suggested that, at 6 weeks after transplantation, blue metachromasia matrixes were observed in tissue; meanwhile, at 12 weeks after transplantation, blue metachromasia matrixes were stronger and stronger in tissue. Results of immunohistochemical staining indicated that, at 6 weeks after transplantation, buffy positive granules were observed in plasma and a few of type-Ⅱ collagen expressed in matrix; meanwhile, at 12 weeks after transplantation, powerfully positive expressions were observed in both plasma and matrix. Expression of type- Ⅱ collage showed that, at 6 weeks after transplantation, dark buffy positive granules were observed in plasma and a few of type- Ⅱ collagen mRNA expressed in matrix; meanwhile, at 12 weeks after transplantation, powerfully positive expressions were observed in both plasma and matrix. Samples in the control group were completely absorbed and any tissue-engineering samples did not form.CONCLUSION: Affecting by osteogenic inducer, rabbit MSCs can generate tissue-engineering cartilage after culture in vitro and in vivo.

Effect of comprehensive rehabilitation on craniocerebral trauma / 中国康复理论与实践

@#ObjectiveTo study the effect of comprehensive rehabilitation on the patients with craniocerebral trauma. Methods85 cases with craniocerebral trauma were subjected to the rehabilitation training supplemented with hyperbaric oxygen and acupuncture and ultrasound therapy in addition to routine neurosurgical operation. Before and after treatment,Glasgow coma scale (GCS), Fugl-Meyer assessment (FMA) and Barthel index were assessed and compared. ResultsAfter comprehensive rehabilitation therapy, the degree of coma, limbs motion and activities of daily living were improved significantly (P<0.01).ConclusionComprehensive rehabilitation is effective on the patients with craniocerbral trauma.

Feixin mixture for vascular remodeling in rats with monocrotaline-induced pulmonary hypertension / 中国组织工程研究

BACKGROUND: Pulmonary hypertension induced by alternation of pulmonary function and structure is the prerequisite of pulmonary-cardiac disorder. Chinese herb, fenxin mixture(FXM) reduces effectively pulmonary hypertension, but the mechanism on which has not been completely explained yet.OBJECTIVE: To comp are the reversal effects between feixin mixture and nifedipine on vascular remodeling in rats with pulmonary hypertension.DESIGN: Randomized controlled experimental study in which experimental animals are taken as the objects.SETTING: Nursing department of affiliated hospital of a medical university;a medical college affiliated hospital and department of traditional Chinese medicine of a provincial hospital.METHODS: Monocrotaline(MCT) (50 mg/kg) was used to duplicate pulmonary-cardiac model in rats. Totally 60 Wister male rats were randomized into 6 groups, namely normal control group, model group, FXM groups of low, middle and high dosages successively and nifedipine group, 10 rats in each group. Since the 14th day of modeling, the corresponding medications were administrated with gastric infusion, continuously for 8 days. After the rats sacrificed, the special staining collaborating with pathological image analysis was used to determine the measurement alternations on path-morphology of pulmonary small artery.wall square(VWS)/total vessel square(TVS), cavity square(CS)/TVS of pulmonary small artery in rats of every group.RESULTS: Both feixin mixture and nifedipine alleviate pulmonary vascular remodeling remarkably( P ＜ 0.01 ), of which, the effect was the best in feixin mixture group of high dosage. But, the every index in experimental groups had not recovered to the level in normal control group completely.CONCLUSION: Feixin mixture reverses partially the remodeling of pulmonary vascular structure and reduces effectively pulmonary hypertension.

Ultrasonic wave in combination with quadriceps exercise for the treatment of senile knee osteoarthritis / 中国组织工程研究

BACKGROUND: The pain and the unstability of the knee joint are the main clinical manifestation of knee osteoarthritis.OBJECTIVE: To verify the efficacy of ultrasonic drug penetration combiued with quadriceps exercise in treating senile knee osteoarthritis.DESIGN: Randomized controlled study.SETTING: Rehabilitation Department of the Affiliated Hospital of Luzhou Medical College.PARTICIPANTS: Seventy-six in-patient and out-patient cases of the knee osteoarthritis, 28 males and 48 females and total 109 knees, were chosen in the Orthopaedic Department and Rehabilitation Department in the Affiliated Hospital of Luzhou Medical College in theperiod between August,2001 and August, 2004. The cases were randomly divided into the experimental group and the control group with 38 cases each.therapy apparatus made in Mianyang was adopted and the diameter of the handpiece was 3 cm. 10 g/L dichloride sodium emulsion (made by Beijing Nuohua Pharmaceutical co.,Ltd) was taken as the coupling agent to smear around the knee joint about 0.75 -1.25 W/cm2, once a day, and 8-10 minutes per time. Meanwhile the static isometric contraction exercise of the knee joint in the extension position was done. Using the quardriceps isometric exercise apparatus, the Delorme progressive resisThe same ultrasonic therapy was done as the therapy group. The nonthermal and microthermal ultrasonic wave was adopted on the suffered location 10 -15 minutes per time, and the tolerance dose of the mid-frequency current was given 20 minutes per time and once a day using the CM-efficacy was assessed in the two groups 4 weeks after the therapy. During the therapy period the anti-inflammatory and analgesic drugs were not patient's knee joint activities of daily life (0 score signifies no pain, 10 scores severe pain, the pain relief better than 40% that before the therapy means the effectiveness). The lower limb activity of daily life was chosen to evaluate the patient's knee joint activities of daily life (5 items,total 10 scores, high score means good, low score means poor). The maximal loading dose in the extension position of the knee joint was measured on the quadriceps isometric exercise apparatus using the suspension weight method.The maximal loading dose in the extension position of the knee joint in the two groups.result of the walking pain scale in the two groups before and after the therapy: The score of pain evaluation after therapy was significantly lower than that before the therapy (P ＜ 0.01), and there was no significant differs knee joint activities of daily life in the two groups before and after the therapy: the result after the therapy was siguifieantly better than that before the therapy, and the efficacy after the therapy was significantly higher than that before the therapy, the efficacy of the experiment group was better than that of the control group (9.61±1.82, 8.77±2.28), while there was tion results of the maximal loading dose in the extension position of the knee joint in the two groups: the result of the experimental group after the therapy was significantly better than that of the experimental group before the therapy and the control group [ (10.05±2.41) kg vs (7.86±1.98) kg and (8.76±1.65) kg, P ＜ 0.01 ].CONCLUSION: The ultrasonic wave using the dichloride sodium emulsion as the ultrasonic coupling agent in combination with quadriceps strengthening exercise in treating the senile knee osteoarthritis is efficacious in relieving pain and improving the ADL ability of the knee joint, increasing the maximal loading dose in the extension position of the knee joint and the stability of the knee joint. The efficacy of the combination therapy is better than the single ultrasonic therapy.

Effect of acupuncture and moxibustion combined with quadriceps exercise on knee osteoarthritis / 中国康复理论与实践

@#Objective To explore the effect of acupuncture and moxibustion combined with quadriceps exercise on osteoarthritis of knee joint. Methods 82 cases of knee osteoarthritis were randomly divided into the acup-moxibustion group (41 cases, treated with acup-moxibustion and quadriceps exercise treatment) and routine treatment group (41 cases). Lower limb ability of daily life respectively and knee pain of patients before and 30 days after treatment were evaluated. Results Clinical symptoms of patients in both groups were improved significantly after treatment. The acup-moxibustion group was better than traditional group in relieving pain and improving the lower limb ability of daily life (P<0.01). Conclusion The acup-moxibustion therapy combined with quadriceps exercise has preferable clinical curative effect on knee osteoarthritis.

Effects of aerobic exercise on quality of life in patients with rheumatoid arthritis / 中华物理医学与康复杂志

Objective To assess the quality of life(QOL) in rheumatoid arthritis(RA) patients treated with 12weeks of aerobic exercise(AE) plus medication(methotrexate, MTX, and NSAIDs). Methods The research design was a randomized controlled trial. The patients in AE group received AE plus MTX and NSAIDs, and the patients in the control group received drug therapy only. Results One hundred and twenty six patients completed the trial, AE patients with improvement of 12%～28% from the baseline were better than medicine treated patients in the physical, social, emotional function, self recognized health status and total QOL. Conclusion AE is effective for the patients with RA in the improvement of QOL.

CT Diagnostic Value of Diffuse Axonal Injury:An Analysis of 45 Cases / 实用放射学杂志

Objective To explore the value of CT in the diagnosis of diffuse axonal injury (DAI).Methods CT signs of 45 cases with DAI were reviewed retrospectioely.Results The diffuse brain edema were found in 45 cases in early stage on CT and small hemorrhage diameter than 2 cm at cerebral hemisphere 18 cases,basal nuclei 10 cases,brainstem 3 cases.Other findings included subarachnoid hemorrhage 21 cases,intraventricular hemorrhage 8 cases,subdural hematoma 7 cases,epidural hematoma 5 cases,and skull fracture 9 cases.Conclusion CT is valuable in diagnosis of DAI.